i had a quick hunt around and it looks like 50-60% of ppl with an isolated case of ON go on to develop MS. i'd see what you can find out about reducing systemic inflammation and supporting a balanced healthy immune system.
Nutrition and optic nerve disease.http://www.ncbi.nlm.nih.gov/pubmed/10159744
The syndrome characterized by papillomacular bundle damage, central or cecocentral scotoma, and reduction of color vision can be produced by toxic, nutritional, or hereditary causes. Patients who present with such a picture should be evaluated for toxic sources such as tobacco or alcohol use. Nutritional deficiencies must be considered and a good family history should be obtained to explore hereditary factors. DNA mutation analysis is available to detect genetic abnormalities. A trial of nutritional replacement may be advisable even in the face of normal laboratory values. Previous reports have shown dramatic visual improvement with intramuscular hydroxocobalamin and other oral vitamin B complexes, even when specific deficiencies are not found.
i can help with nutrition stuff if you like.
more reading on the various, often quite manageable things that can be linked to ON, besides MS..:http://xa.yimg.com/kq/groups/21616406/1 ... optica.pdf
my approach: no meds so far - just nutrient-dense anti-inflammatory whole foods, and supplements where needed
info: www.whfoods.com, www.nutritiondata.com