I'm planning a new study, and would appreciate your feedback. Can you ever "anticipate" relapse? If so, what are the warning signs, and how many hours/days ahead of the event can you feel like it might be coming on?
Your feedback would be really helpful for my study design. I'm trying to find biomarkers that would warn you of an impending relapse before you feel sick.
About me: I'm Jacob Glanville, a computational immunologist at Stanford and CSO of Distributed Bio. I've developed some novel techniques for using genomics technologies to monitor the immune system, and have applied it to identical twins that were discordant to multiple sclerosis previously:
J Glanville*, T Kuo*, HC von Büdingen* et al, “Naive antibody gene-segment frequencies are heritable and unaltered by chronic lymphocyte ablation”,Proceedings of the National Academy of Sciences, 2011
HV Büdingen, T Kuo, S Marina, C Belle, L Apeltein, J Glanville et al. “B cell exchange across the blood-brain barrier in multiple sclerosis.” The Journal of Clinical Investigation 122.12 (2012): 4533.