Luongo wrote:Can anyone explain to a terribly impatient plebian like myself why for the last X amount of years there seem to be studies every 5 months or so about remyelination, usually peppered with hope-raising language like 'groundbreaking' and 'promising' and none of it ever seems to amount to anything?
A VERY good question, Luongo.
Being the skeptic that I am, I have wondered for a long time if the time and money spent on remyelination research was a waste. After all, the lesions are scar tissue which the body has made to fix damage. I have scars on my legs and torso where other injuries healed. The skin on my legs and torso functions just fine with scars. I know that some scars, such as from burns, do not allow for normal function. BUT which is the situation for scars in the CNS? Why are researchers convinced that the symptoms in MS are due to these scars, and NOT due to a problem in the muscles themselves (such as insulin resistance inhibiting the energy source, glucose, from reaching the cell's mitochondria)?
I think researchers are looking in the wrong box of keys for THE key which will unlock this prison of MS.