Niacin B3

If it's on your mind and it has to do with multiple sclerosis in any way, post it here.

Re: Niacin B3

Postby jimmylegs » Fri May 16, 2014 4:19 pm

odd, i would have though ffa status would be positively correlated with the strength of the flush.

A volumetric biochemical niacin flush-based index that noninvasively detects fatty acid deficiency in schizophrenia
http://www.sciencedirect.com/science/article/pii/

Relationship between the niacin skin flush response and essential fatty acids in schizophrenia
http://www.sciencedirect.com/science/ar ... 7803001650

Eicosapentaenoic acid in treatment-resistant depression associated with symptom remission, structural brain changes and reduced neuronal phospholipid turnover
http://europepmc.org/abstract/MED/11695 ... jjQa5Th.24
"The n-3 essential fatty acid eicosapentaenoic acid (EPA) was added to the conventional antidepressant treatment of a treatment-resistant severely depressed and suicidal male patient with a seven-year history of unremitting depressive symptoms. The niacin skin flush test and cerebral magnetic resonance scanning were carried out at baseline and nine months later. The addition of ethyl-EPA led to a dramatic and sustained clinical improvement in all the symptoms of depression, including a cessation of previously unremitting severe suicidal ideation, within one month. Symptoms of social phobia also improved dramatically. During the nine-month period the volumetric niacin response increased by 30%..."
jimmylegs
Volunteer Moderator
 
Posts: 9033
Joined: Sat Mar 11, 2006 4:00 pm

Advertisement

Re: Niacin B3

Postby zjac020 » Sat May 17, 2014 1:04 am

way out of my league jimmy...now im completely lost
zjac020
Family Elder
 
Posts: 137
Joined: Tue Aug 20, 2013 12:50 pm

Re: Niacin B3

Postby jimmylegs » Sat May 17, 2014 6:45 am

just responding to thx's point 2
jimmylegs
Volunteer Moderator
 
Posts: 9033
Joined: Sat Mar 11, 2006 4:00 pm

Re: Niacin B3

Postby THX1138 » Sat May 17, 2014 9:38 am

jimmylegs wrote:odd, i would have though ffa status would be positively correlated with the strength of the flush.

A volumetric biochemical niacin flush-based index that noninvasively detects fatty acid deficiency in schizophrenia
http://www.sciencedirect.com/science/article/pii/

Relationship between the niacin skin flush response and essential fatty acids in schizophrenia
http://www.sciencedirect.com/science/ar ... 7803001650

Eicosapentaenoic acid in treatment-resistant depression associated with symptom remission, structural brain changes and reduced neuronal phospholipid turnover
http://europepmc.org/abstract/MED/11695 ... jjQa5Th.24
"The n-3 essential fatty acid eicosapentaenoic acid (EPA) was added to the conventional antidepressant treatment of a treatment-resistant severely depressed and suicidal male patient with a seven-year history of unremitting depressive symptoms. The niacin skin flush test and cerebral magnetic resonance scanning were carried out at baseline and nine months later. The addition of ethyl-EPA led to a dramatic and sustained clinical improvement in all the symptoms of depression, including a cessation of previously unremitting severe suicidal ideation, within one month. Symptoms of social phobia also improved dramatically. During the nine-month period the volumetric niacin response increased by 30%..."


Thanks JL. :-D I just amended that post.
Below is part of what I was talking about:
The circadian rhythm of iMg2+ was found to be considerably more pronounced than that of total Mg and was negatively correlated to changes of free fatty acids.
http://www.ncbi.nlm.nih.gov/pubmed/7578617
THX1138
Family Elder
 
Posts: 442
Joined: Tue May 14, 2013 3:00 pm

Re: Niacin B3

Postby jimmylegs » Sat May 17, 2014 10:23 am

ok so the inverse correlation is between variation in circadian rhythm, and 'changes' of free fatty acid. i would definitely need to see full text to get a real handle on what that sentence is actually saying!
jimmylegs
Volunteer Moderator
 
Posts: 9033
Joined: Sat Mar 11, 2006 4:00 pm

Re: Niacin B3

Postby Scott1 » Sat May 17, 2014 3:03 pm

This is a good discussion but if we go back to the original proposition aren't you just trying to improve vasodilation?

I would use L-arginine to dilate the blood vessels and coenzyeme Q10 to improve the quality of the blood cells. That would be part of a bigger protocol which I have set out here - regimens-f22/topic24019.html

The Niacin seems like using a hammer to open screwtop jars to me. It just depends how many jars you have.
The fumurate esters are interesting but if you go back a step you will be looking at arginine so why not start there?

Regards
User avatar
Scott1
Family Elder
 
Posts: 419
Joined: Wed Oct 22, 2008 3:00 pm

Re: Niacin B3

Postby jimmylegs » Sat May 17, 2014 3:43 pm

i personally used niacin early on, to improve blood flow for better oxygen and nutrient delivery. it was a factor in the klenner protocol for ms which did me so much good. for years upon years prior to dx, as a vegan, i would not necessarily have had the best niacin status. so in the early days it made sense. but i switched to omnivore basically a few minutes after getting diagnosed. now i'm pretty sure i have plenty in my system. http://www.whfoods.com/genpage.php?tnam ... #foodchart
i have read that the concerns over supplemental niacin's potential damage to the liver are exaggerated, but personally, it's still not something i would bother taking as a long term thing.
jimmylegs
Volunteer Moderator
 
Posts: 9033
Joined: Sat Mar 11, 2006 4:00 pm

Previous

Return to General Discussion

Who is online

Users browsing this forum: No registered users


Contact us | Terms of Service