you may be right that it starts slowly..
But I think the acute relapse is more an issue of receptor blocking by Cpn or EBV.
all this is possible because BBB broke as result of many years of ccsvi.
In my case I recovered four times taking antibiotics, without knowing I had MS.
I was diagnosed only at 47, after mid age.
I see the E-toxin hypothesis as a plausible candidate for the progressive form.
The permeable gut which absorbs 35 k Da E-toxin only starts as of mid-age...
please look at the last two postings on general-discussion-f1/topic15188.html
the first posting on pg 1 is my best assessment of what is MS.
the toxin is Epsilon protoxin, produced by an unbalanced gut micro-biome, and more in particular by Clostridium Perfringens type B bacteria.
and can leak into the circulation because as of mid age the gut lining breaks (e.g. due to food intolerance ..)