tzootsi wrote:What is MRF-008? Myelin Repair Foundation's substance #8? Could it be Lisinopril which is used for treating hypertension and has been looked at as a treatment for MS?
An inexpensive blood pressure medication and ACE inhibitor which modulates angiotensin. This drug opens up blood vessels and allows blood to flow more easily. This older drug is being developed to treat MS by Dr. Lawrence Steinman of Stanford University School of Medicine. (Dr. Steinman is also one of the inventors of Tysabri--which he has since spoken out against as a first line treatment for MS.)
... angiotensin immediately causes blood vessels to constrict. “That raises your blood pressure so when you stand up to get out of a chair, you don’t fall down and faint,” said Steinman, who is also the George A. Zimmerman Professor in the medical school. But angiotensin overactivity causes chronic hypertension. Lisinopril controls blood pressure by blocking an enzyme that converts angiotensin’s precursor into the active hormone. The drug also appears to have certain anti-inflammatory properties.
Azaeleaprawn wrote:A while ago I read somewhere that the hypertension drug Captopril helped - wonder if it's the one.
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