I agree with you and the Australian article, that Vitamin is a factor for developing MS, and is not a singular cause. If vitamin D deficiency alone caused MS, a much larger percentage of the world would have MS, as Vitamin D deficiency is pretty pervasive all over the world. However, there appears to be several lines of evidence that increasing Vitamin D levels.
It is hurricane season again in my corner of the globe. I think of MS like a hurricane - several factors have to come together, like warm water, favorable wind patterns, lack of a competing weather system, etc. to allow a hurricane to form. I'm sure a meteorologist could come up with several more. If just one important factor is missing (warm water), there is no hurricane. It is probable that vit D deficiency is one of the contributors to MS, but not alone.
My sentiments exactly LisB. Predisposition + abundant causal factors+ deficincy of vit D.
However I think it is quite evident that vitamin D is overwhelmingly the most influential of these components. So much so that it is not stretching fact to ascertain that a deficiency of vitamin D is the cause of MS in predisposed folks. From a preventative perspective, the existing data implies vitamin D is unsurpassed in effectiveness for preventing MS. The problem here is that there is little emphasis placed on prevention and of course the absence of a financial motive.
Muslim women that keep covered and that live in the London have been shown to be vitamin D deficient. I can't find this research paper on the DIRECT-MS site since it was reorganized though. Consider that Muslim women might not be susceptible, hence a D deficiency wouldn't necessarily be expressed as MS, however other conditions of D deficiency would.
There's also the issue of timing of vitamin D abundance and disease formation. Covered Muslim women weren't born with a cloak on you know;)
PS I’m not an expert but I’m sure that the majority of nuns don't wear the gothic garb of tradition anymore
You might find this article below of interest.
Mortality from multiple sclerosis and exposure to
residential and occupational solar radiation:
a case-control study based on death certificates
Objectives—To explore whether mortality from multiple sclerosis is negatively associated
with exposure to sunlight.
Methods—Two case-control studies based on death certificates were conducted for
mortality from multiple sclerosis and non-melanoma skin cancer (as a positive
control) to examine associations with residential and occupational exposure to
sunlight. Cases were all deaths from multiple sclerosis between 1984 and 1995 in 24
states of the United States. Controls, which were age frequency matched to a
series of cases, excluded cancer and certain neurological deaths. The effects of
occupational exposure to sunlight were assessed among subjects with usual occupations
requiring substantial activity, so
as to exclude those whose indoor jobs resulted from disabilities subsequent to
the onset of the disease. Multiple logistic regression analyses were applied, with
adjustment for age, sex, race, and socioeconomic status.
Results—Unlike mortality from skin cancer, mortality from multiple sclerosis was
negatively associated with residential exposure to sunlight (odds ratio (OR)=0.53
(multiple sclerosis) and OR=1.24 (skin cancer)). Odds ratios for the highest
occupational exposure to sunlight were 0.74 (95% confidence interval (95% CI)
0.61 to 0.89) for mortality from multiple sclerosis, compared with 1.21 (1.09 to 1.34)
for mortality from non-melanoma skin cancer. The OR was 0.24 for the combined
effect of the highest levels of residential and occupational exposure to sunlight on
multiple sclerosis, compared with an OR of 1.38 for skin cancer.
Conclusions—In this exploratory study, mortality from multiple sclerosis, unlike
mortality from skin cancer, was negatively associated with both residential and occupational
exposure to sunlight.
(Occup Environ Med 2000;57:418–421)
Keywords: multiple sclerosis; aetiology;