omfg, again! closed a different program and the whole set of browser windows went as well. grr.
so. one more time... :S given this:
serum vitamin 25(OH)vitaminD3: aim for at least 100 nmol/L (40 ng/mL). preferably 125-150 nmol/L (56-60 ng/mL). ...
i don't think you're in terrible shape at 37 ng/mL. what's your regimen been like, altogether? if you push higher with the d3, i'd hope you could get some mineral cofactor levels looked at as well.
re the switch up during summer, here's some relevant research for healthy controls
In vivo threshold for cutaneous synthesis of vitamin D3http://www.ncbi.nlm.nih.gov/pubmed/2549141
"The minimal UVB radiation level that produced a significant increase in serum vitamin D3 was 18 mJ/cm2, a value similar to the lowest solar broadband UVB irradiance that generates previtamin D3 in vitro from the precursor 7-dehydrocholesterol (20 mJ/cm2)."
Influence of season and latitude on the cutaneous synthesis of vitamin D3: exposure to winter sunlight in Boston and Edmonton will not promote vitamin D3 synthesis in human skinhttp://www.ncbi.nlm.nih.gov/pubmed/2839537
"Human skin or [3 alpha-3H]7-dehydrocholesterol exposed to sunlight on cloudless days in Boston (42.2 degrees N) from November through February produced no previtamin D3. In Edmonton (52 degrees N) this ineffective winter period extended from October through March."
fun local calculator:
VitD-ez Duration of Vitamin D Synthesis in Human Skinhttp://nadir.nilu.no/~olaeng/fastrt/VitD-ez.html
things to note regarding the less healthy, (in these studies, FM patients - who share some of the same issues with vit d3 cofactors as we see in the average ms patient):
The relationship between serum trace element levels and clinical parameters in patients with fibromyalgiahttp://link.springer.com/article/10.100 ... 008-0593-9
"Serum levels of zinc (P = 0.001) and magnesium (P = 0.002) were significantly decreased ... Association between serum zinc level and number of tender points (P = 0.008) and that between fatigue and magnesium level (P = 0.003) was found as meaningful. According to the results of this study, it was asserted that serum magnesium and zinc levels may play an important role in the pathophysiology of FM
Bone mass and vitamin D levels in women with a diagnosis of fibromyalgiahttp://link.springer.com/article/10.100 ... 013-2434-2
"25OHD levels were also similar: 23.0 ± 9.5 ng/ml and 24.1 ± 9.6 ng/ml. [JL edit: similar, yes. healthy, no] However, while controls showed the usual summer rise in 25OHD, fibromyalgia patients did not
pretty fascinating stuff
my approach: no meds so far - just nutrient-dense anti-inflammatory whole foods, and supplements where needed
info: www.whfoods.com, www.nutritiondata.com