Positive top-line results in phase III Daclizumab high-Yield

If it's on your mind and it has to do with multiple sclerosis in any way, post it here.

Positive top-line results in phase III Daclizumab high-Yield

Postby MSUK » Mon Jun 16, 2014 6:58 am

Positive top-line results in phase III Daclizumab high-Yield process study in MS

Biogen Idec and AbbVie ABBV announced positive top-line results from the Phase 3 DECIDE clinical trial, designed to evaluate the superiority of once-monthly, subcutaneous daclizumab high-yield process (DAC HYP) when compared to intramuscular interferon beta-1a (IFN β-1a), as a potential treatment for relapsing-remitting multiple sclerosis (RRMS), the most common form of multiple sclerosis (MS). Results showed that DAC HYP was superior on the study’s primary endpoint, demonstrating a statistically significant 45 percent reduction in annualized relapse rate (ARR) compared to IFN β-1a (p<0.0001)....... Read More - http://www.ms-uk.org/zenapax
MS-UK - http://www.ms-uk.org/
User avatar
MSUK
Family Elder
 
Posts: 2145
Joined: Wed Oct 14, 2009 3:00 pm

Advertisement

Re: Positive top-line results in phase III Daclizumab high-Y

Postby HarryZ » Mon Jun 16, 2014 5:00 pm

MSUK wrote:Positive top-line results in phase III Daclizumab high-Yield process study in MS

Biogen Idec and AbbVie ABBV announced positive top-line results from the Phase 3 DECIDE clinical trial, designed to evaluate the superiority of once-monthly, subcutaneous daclizumab high-yield process (DAC HYP) when compared to intramuscular interferon beta-1a (IFN β-1a), as a potential treatment for relapsing-remitting multiple sclerosis (RRMS), the most common form of multiple sclerosis (MS). Results showed that DAC HYP was superior on the study’s primary endpoint, demonstrating a statistically significant 45 percent reduction in annualized relapse rate (ARR) compared to IFN β-1a (p<0.0001)....... Read More - http://www.ms-uk.org/zenapax



Hmmm..another monoclonal antibody(no long term side effects known) that hangs its hat on a reduction of white matter lesions (which don't correlate with MS symptoms) and elevates liver enzymes 6 times above normal!! Another Tysabri in the making?
User avatar
HarryZ
Family Elder
 
Posts: 2557
Joined: Tue May 25, 2004 3:00 pm
Location: London, ON, Canada


Return to General Discussion

 


  • Related topics
    Replies
    Views
    Last post

Who is online

Users browsing this forum: No registered users


Contact us | Terms of Service