Risk of MS increased by low testicular function

If it's on your mind and it has to do with multiple sclerosis in any way, post it here.
Post Reply
User avatar
MSUK
Family Elder
Posts: 2903
Joined: Wed Oct 14, 2009 2:00 pm
Contact:

Risk of MS increased by low testicular function

Post by MSUK »

Testicular hypofunction and multiple sclerosis risk: A record-linkage study.

Pakpoor J, Goldacre R, Schmierer K, Giovannoni G, Goldacre MJ.

Abstract

The influence of gonadal hormones on multiple sclerosis is not well characterised and has thus far been investigated primarily in animal models or as a proposed therapeutic approach.

We investigated a potential association between testicular hypofunction, as a proxy for low testosterone levels, and multiple sclerosis risk through analysis of linked English national Hospital Episode Statistics from 1999 to 2011.
We report a strong positive association between testicular hypofunction and subsequent multiple sclerosis, rate ratio 4.62 (95% confidence interval 2.3-8.24, p<0.0001).

Future work should aim more directly to elucidate the relationship between testosterone levels and MS in both males and females.

Source: ANN NEUROL 2014. © 2014 American Neurological Association & Pubmed 25131454 (21/08/14) http://www.ms-uk.org/hormones
MS-UK - http://www.ms-uk.org/
Post Reply
  • Similar Topics
    Replies
    Views
    Last post

Return to “General Discussion”