Vitamin A & D use same receptor

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Vitamin A & D use same receptor

Postby lyndacarol » Thu Nov 10, 2016 2:05 pm

Vitamin D Prevents Cancer: Is It True? (30 min) 2009
Carole Baggerly & Cedric F Garland, Dr.P.H., FACE, UC, San Diego, Moores Cancer Center
https://www.youtube.com/watch?v=TQ-qekFoi-o

Baggerly speaks first; Garland begins @18:53 (https://youtu.be/TQ-qekFoi-o?t=1133 )

@24:58 Slide: Unfortunately, Vitamin A and D use the same receptor, it's known as the vitamin A and D heterodimer receptor. And if vitamin A gets on board, vitamin D has a hard time getting on board and the effect of vitamin D is diminished. It's competition at the receptor level so you want to keep your vitamin A intake below 6000 IU/day. It's just not necessary to take a high amount of vitamin A and actually is counterproductive. Cod liver oil, unfortunately, contains both vitamin A and D so you can't really get to affective levels for cancer prevention, or it's nearly impossible, with vitamin A interfering with the effect of vitamin D which occurs in cod liver oil, so you're looking for something that contains only vitamin D3, cholecalciferol, as long as you're at the usual intake level of vitamin A. A thousand\ international units a day really would meet those requirements.

@27:29 We metabolize, according to Dr. Robert Heaney and his colleagues, almost 5,000 international units a day of vitamin D, so we go through it quite rapidly and we’re very depleted by March.
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