Lyon wrote:With the possibility of entering the clinical trial starting to seem like a reality, I'm seeking input from the thisisms braintrust........yes, this means YOU!
I also have hopes that something will come of Tovaxin. The information that I've read on it seems promising and it's one of the few treatments for MS that really makes sense to me. Nearly all people have some autoimmune T cells. See the following paper in Nature Reviews Immunology
for an interesting discussion. One of the problems in people with MS is that these autoreactive T cells are not regulated well and are allowed to persist. It would be great if a vaccine such as Tovaxin could retrain the immune system to eliminate just those T cells which attack myelin. Now with respect to news about Tovaxin, you can always read the research articles linked to on Opexa's
website. In addition, here's a link
to one of my threads where I posted a link to an interview with David McWilliams the then CEO of Pharmafrontiers.
I sincerely wish your wife the best if she is accepted into the Tovaxin trial. If I was starting over again freshly diagnosed, then it would be high on my list of considerations. Lastly, with respect to your wife's liver problems with IFN-B, if she ever considers going back on it, then you may want to look into supplements which have been reported to help the liver. Some of these include antioxidants such as n-acetyl cysteine and epigallocatechin gallate (EGCG) from green tea.