Tropospheric ozone

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Tropospheric ozone

Postby Petr75 » Mon Jan 30, 2017 11:35 am

Hello friends, I ask for opinion ..


I dare theory
Ozone as a possible cause of MS

What's going on?
wiki https://en.wikipedia.org/wiki/Tropospheric_ozone

Possible clues:
Image

Image
New Guinea and MS - rarity ?? https://www.ncbi.nlm.nih.gov/pubmed/8266734

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Prevalence MS, vitamindwiki.com
Image


Total ozone, appinsys.com
Image

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addendum:

https://www.ncbi.nlm.nih.gov/pubmed/28099554
No correlation was observed between vitamin D levels and disability of patients with multiple sclerosis between latitudes 18° and 30° South.

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CCSVI 2012 Ostrava
Currently tecfidera
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Re: Tropospheric ozone

Postby ElliotB » Mon Jan 30, 2017 1:04 pm

And what caused MS when ozone was not an issue like it appears it might be today?

MS has been around for a long, long time...

But it is a good theory, as good as any other!
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Re: Tropospheric ozone

Postby Petr75 » Wed Feb 01, 2017 12:34 am

Yes good question but ozone been there before:
Volcanic activity, fires..


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Image
source http://www.neurology.org/content/61/10/ ... nsion.html




Image

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just speculation
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Re: Tropospheric ozone

Postby Petr75 » Mon Oct 16, 2017 7:54 am

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Re: Tropospheric ozone

Postby Petr75 » Sun Dec 31, 2017 11:50 pm

ElliotB wrote:And what caused MS when ozone was not an issue like it appears it might be today?

MS has been around for a long, long time...

But it is a good theory, as good as any other!


2017 Dec 29
Impacts of fire smoke plumes on regional air quality, 2006-2013
https://www.ncbi.nlm.nih.gov/pubmed/29288254

The fires were here before humans
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Re: Tropospheric ozone

Postby David1949 » Mon Jan 01, 2018 6:02 pm

Maybe you have a correlation between ozone and MS. But a correlation does not prove cause and effect. You need more than that.
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Re: Tropospheric ozone

Postby Petr75 » Tue Jan 02, 2018 8:46 am

David1949 wrote:Maybe you have a correlation between ozone and MS. But a correlation does not prove cause and effect. You need more than that.

Yes, maybe it's crap, maybe not.

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MS/day
In the morning and at night I'm relatively ok. During the day ko. I'm not alone with this problem. For example: https://www.msconnection.org/Blog/Octob ... dic-Skiing
And rainy - I'm ko.

O3
Image

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MS/month
https://www.ncbi.nlm.nih.gov/pubmed/21040535

O3 - https://www.researchgate.net/figure/Sea ... _223219182
Image
(Hawaii, https://www.researchgate.net/figure/Sea ... _223219182 )

Data from our areas needs to be documented. It does not have to sit.
Possible satellite https://www.youtube.com/watch?v=AyC0cxVqXjQ
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PM10
Air pollution by particulate matter PM10 may trigger multiple sclerosis relapses. https://www.ncbi.nlm.nih.gov/pubmed/28407574

Ozone and PM10 https://cfpub.epa.gov/ncer_abstracts/in ... leID/14128
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MMP-12 https://www.ncbi.nlm.nih.gov/pubmed/28155200
MMP-12/O3 https://www.ncbi.nlm.nih.gov/pubmed/21355040
Induction of stress proteins and MMP-9 by 0.8 ppm of ozone in murine skin https://www.ncbi.nlm.nih.gov/pubmed/12763055
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SP-A2 contributes to miRNA-mediated sex differences in response to oxidative stress: pro-inflammatory, anti-apoptotic, and anti-oxidant pathways are involved. https://www.ncbi.nlm.nih.gov/pubmed/29202868
The air of Europe: where are we going? https://www.ncbi.nlm.nih.gov/pubmed/29212835

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PubMed https://ereska.net/viewtopic.php?f=39&t=1837
Environment https://ereska.net/viewtopic.php?f=40&t=2383
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10/09/2012
Max Planck Institute of Neurobiology
Multiple sclerosis is remote controlled
The lungs function as a gathering point for autoaggressive immune cells https://www.mpg.de/6346184/multiple_sclerosis-lungs
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The relationship with O3 is a theory !!!!!!!!!!!!!!!!!!!
I'm not a doctor or a scientist
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Re: Tropospheric ozone

Postby jimmylegs » Tue Jan 02, 2018 11:44 am

lots of varied associations between x and y in all kinds of multifactorial chronic illnesses.

sensitivity may in part be secondary to pre-existing insufficiencies and related dysfunction

for any worried plant lovers:

Manganese deficiency enhances ozone toxicity in bush beans (Phaseolus vulgaris L. cv. Saxa) (1996)
http://www.sciencedirect.com/science/ar ... 1796803087

Zinc deficiency enhances ozone toxicity in bush beans (Phaseolus vulgaris L. cv. Saxa) (1995)
https://academic.oup.com/jxb/article-ab ... 867/570212

Effects of cadmium (JL: aka anti-zinc) and zinc on ozone-induced phytotoxicity in cress and lettuce (1974)
http://www.nrcresearchpress.com/doi/abs ... kvb8lWnG70
"Cress plants that had received soil application of cadmium showed markedly increased ozone-induced phytotoxicity in terms of visible leaf damage and pigment degradation; in lettuce, only pigment degradation was evident based on chlorophyll analysis. Soil application of zinc showed less ozone-induced phytotoxicity on cress and no pigment degradation in lettuce."

not forgetting the rat lovers:

Zinc nutritional status and response to lethal level of ozone exposure in rats (1979)
https://www.osti.gov/scitech/biblio/5175381
"...The present study, however, showed that zinc supplementation of animals cannot provide protection from ozone induced lung damage simply because zinc does not accumulate in the lung tissues, the primary target organ for ozone damage."

on to humans.

Nutrition and lung health (2005)
https://www.ncbi.nlm.nih.gov/pubmed/15830741
"Several lung diseases have been associated with oxidative stress and linked to oxidant insults such as cigarette smoke, air pollutants and infections. Consequently, dietary factors and nutrients with a potential protective role in the oxidative process and inflammatory response have been implicated in the genesis or evolution of these diseases. These nutrients include fruits and vegetables, antioxidant vitamins such as vitamin C, vitamin E, betacarotene and other carotenoids, vitamin A, fatty acids and some minerals such as sodium, magnesium and selenium. This article reviews the potential mechanisms by which dietary factors may affect respiratory health, and discusses epidemiological evidence for the link between diet and lung diseases. Most of the available evidence on the effect of dietary factors on the risk for obstructive lung diseases are derived from cross-sectional studies. These studies suggest that antioxidant vitamins, particularly vitamin C, and to a lesser extent other antioxidants, have a protective effect against lung diseases. However, the few intervention studies have not been conclusive. High intake of fresh fruit and some vegetables appears to have a beneficial effect on lung health and their consumption should be recommended on a daily basis. Supplementation of vitamin C and other antioxidants could be proposed in subjects with additional oxidative stress challenge, such as exposure to high levels of air pollution. Subjects with impaired immune response could also benefit from vitamin A and zinc supplementation. Further studies are needed to determine the impact of diet on the incidence and evolution of lung diseases."

might also be worth a read:

Is it true that ozone is always toxic? The end of a dogma (2006)
http://www.sciencedirect.com/science/ar ... 8X06002195
odd sx? no dx? check w/ dietitian
DRI=MINIMUM eg bit.ly/1vgQclQ
99% don't meet these. meds/lifestyle can affect levels
status can be low in ms & other cond'ns
'but my results are normal'. typical panels don't test all
deficits occur in 'normal' range
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Re: Tropospheric ozone

Postby koneall » Wed Jan 03, 2018 8:04 am

Ozone tends to be connected to air pollution. When there's more smog, there's more ozone. Smog is a mixture of carbon, sulphur and nitrogen atoms. Ozone can be smelled in the air after a rain storm. Ozone is the twenty mile layer of the outer atmosphere. It deflects rays of light, protecting from radiation damage. Small amounts of ozone inhaled stimulates the antioxidants in the body.
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Re: Tropospheric ozone

Postby Petr75 » Wed Jan 03, 2018 12:38 pm

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Re: Tropospheric ozone

Postby jimmylegs » Wed Jan 03, 2018 1:17 pm

Image
odd sx? no dx? check w/ dietitian
DRI=MINIMUM eg bit.ly/1vgQclQ
99% don't meet these. meds/lifestyle can affect levels
status can be low in ms & other cond'ns
'but my results are normal'. typical panels don't test all
deficits occur in 'normal' range
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Re: Tropospheric ozone

Postby Petr75 » Thu Jan 04, 2018 12:03 am

Food can be a strong answer to MS (EAE) https://translate.google.cz/translate?s ... edit-text= Cz https://ereska.net/viewtopic.php?f=17&t=237

But
how long can a man last without food and how long without breathing ?...
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2017
The influence of solar and geomagnetic activity on the risk of multiple sclerosis (results of correlation and regression analysis)
https://www.ncbi.nlm.nih.gov/pubmed/28617360

2015
Geomagnetic field and climate: Causal relations with some atmospheric variables https://link.springer.com/article/10.11 ... 1315050067
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Re: Tropospheric ozone

Postby Petr75 » Sun Feb 11, 2018 3:00 am

2018 Feb 15
Hamamatsu University School of Medicine, Japan
Neuroinflammation following disease modifying therapy in multiple sclerosis: A pilot positron emission tomography study
https://www.ncbi.nlm.nih.gov/pubmed/29406909
CONCLUSIONS:
The current results indicate that microglial activation may proceed in the entire brain of clinically stable MS patients even after receiving DMT.

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2016 May;30(5)
Indiana University School of Medicine, USA
Microglial priming through the lung-brain axis: the role of air pollution-induced circulating factors
https://www.ncbi.nlm.nih.gov/pubmed/26864854 Full https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4836369/
..Together, these findings outline the lung-brain axis, where air pollutant exposures result in circulating, cytokine-independent signals present in serum that elevate the brain proinflammatory milieu, which is linked to the pulmonary response and is further augmented with age.
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Re: Tropospheric ozone

Postby Petr75 » Sat Feb 17, 2018 7:29 am

2018 Feb 6
EHESP French School of Public Health, Sorbonne Paris Cité, Rennes, France
Ozone, NO2 and PM10 are associated with the occurrence of multiple sclerosis relapses. Evidence from seasonal multi-pollutant analyses.
https://www.ncbi.nlm.nih.gov/pubmed/29426027
.. However, using multi-pollutant models, only O3 remained significantly associated with the odds of relapse triggering during "hot" season.

CONCLUSION:We observed significant single-pollution associations between the occurrence of MS relapses and exposures to NO2, O3 and PM10, only O3 remained significantly associated with occurrence of MS relapses in the multi-pollutant model.
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Re: Tropospheric ozone

Postby koneall » Sat Feb 17, 2018 7:46 am

I believe the stratosphere is 20-50 miles above the earth. It's protective, not injurious. Ozone medical therapy was common in the 20's, 30's and early 40's. Once penicillin was discovered ozone generators were consigned to the waste bins. But these days there are infections that are resistant to all antibiotics. But not resistant to ozone. I use ozone daily in my veterinary practice. It enhances oxygen dispersal from hemoglobin to tissues. It allows mitochondria to function more effectively. It destroys microbes on contact. Ozone in the air is linked to air pollution mainly because it's easily tested for. But not because the ozone has anything to do with smog. Perhaps it's the smog that's causing an increase in MS cases.
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