Double dosing

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Double dosing

Postby bromley » Tue Sep 19, 2006 10:18 am

If a drug doesn't work that well - the solution is to double the dose! But this doesn't apply to Copaxone.

http://www.msanswers.ca/QuestionView.aspx?L=2&QID=241
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Postby Brownsfan » Tue Sep 19, 2006 10:47 am

Funny that this doctor thinks that doubling up on interferon is fine but "there is no data or rationale to consider doing this for glatiramer acetate". I found this statement odd until I saw the disclaimer on the side of the page that stated:

"The MS Society of Canada gratefully acknowledges the support of Biogen Idec for an unrestricted education grant which makes possible the Ask the Expert series."

Thanks but I'll get my advice from an unbiased source.

J
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Postby amelia » Tue Sep 19, 2006 11:28 am

Ian,
I've got one better. Read my post in Tysabri forum for full details. Gary's DR is wishy washy about putting him on Tysabri, but was more than anxious to put him on a double dose of Betaseron with a high dose of steroids to begin with to "lessen" the antibody reaction. Gary developed the antibodies and couldn't take the interferons. Besides, he was horribly ill every other day the whole time he was on Betaseron. But he should be concerned about Tysabri! ha She even mentioned Novantrone to him. Read the side effects to that one! If 1 dose of interferons can be bad on your liver, what does the double dose do in time. I suspect some CRAB's are fighting tooth and nail to stay afloat
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staying afloat

Postby gwa » Tue Sep 19, 2006 1:59 pm

Amelia, I agree about the CRAB companies trying to stay afloat. I thought it was amusing (my sense of humor is rather dark) that TEVA was investigating the interferons now to find out about the NABS problems.

Why they don't use their funds to come up with a really great product is mindboggling to me.

I am TIRED of "news" about any of the CRABS. They don't work for most of RRMS'ers and they don't do boo for those of us that are SPMS or PPMS.

gwa
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Postby amelia » Tue Sep 19, 2006 2:22 pm

Gary's recent brain MRI is somewhat proof in the pudding.
He had 5 OLD lesions in over a year ago. To the best of our knowledge, he doesn't have anything new, if any.
He was on Copaxon last year about every other day to every 3 or 4 days and then tapered to Not hardly at all in Nov and Dec 2005. He stopped altogether in Jan 2006. Now I would consider that as LESS Copaxon, not more.
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