Scientists reveal the workings of key molecular mechanism

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Scientists reveal the workings of key molecular mechanism

Postby MSUK » Thu Jan 18, 2018 8:17 am

Scientists reveal the workings of key molecular mechanism of autoimmune and inflammatory diseases

An international team of researchers led by Professor Savvas Savvides, VIB-UGent Center for Inflammation Research, has unravelled a crucial aspect of the molecular basis of autoimmune and inflammatory diseases such as multiple sclerosis, psoriasis, rheumatoid arthritis and Crohn's disease. Focusing on the immunomodulatory cytokine IL-23 they discovered that its pro-inflammatory activity, which underlies a wide range of inflammatory diseases, critically depends on structural activation of the cytokine by its receptor, IL-23R. The results of the study are published in the leading journal Immunity...Read more - http://www.ms-uk.org/scientists-reveal-workings-key-molecular-mechanism-autoimmune-and-inflammatory-diseases

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