This Is MS Multiple Sclerosis Community: Knowledge & Support

has your wife tried antibiotics, ldn , vitamins, lipitor, ect please let me know if she found any of these helpful. she has hade ms for a long time and i just wondered. thx

Becca.



Sorry I missed your message and didn't see it until today.

Marg tried LDN for about a year but found no difference, one way or the other to her condition. She discontinued its use after that time.

The only medication that she has been on for her MS the past 6 1/2 years has been Prokarin. It has relieved a number of her symptoms and kept her head above water for this time. She has used Lyrica sparingly for the past year to help with her spasms and related pain.

Take care.

Harry

Harry, I tried prokarin, but it didnt work for me. However, when I do a niacin flush, i get very itchy all over. I have read that this is because of a release of histamine. At first I thought nothing of it since it was just to my skin, but then it occured to me that prokarin is a patch applied to the skin.

Has your wife tried a niacin flush? did she notice anything?

I would not really recommend it as maybe it drains the rest of your system of histamine. The itch fades with each niacin flush.

Cure,



That's too bad about the lack of success with Prokarin...about 1/3 of the users have no reaction at all to it. That's about the worst case scenario with side effects.....nothing happens!

If the Prokarin patch is applied properly (air tight) you should not have any skin irritation at all. When the drug starts to metabolize, H2 neruo receptors are produced and this is what allows your cells to function properly.....a process that is lacking in many MS patients. Only when air and/or water is allowed to mix with the histamine diphosphate do you get H1 receptors and those are the ones that cause allergic reactions etc.



No she hasn't and this is the first time I have ever heard of this.

Harry

i haven't done one in a while but yea if you get niacinamide, no flush. straight niacin, flush city. i have to take a maybe three of my niacin pills to get it going. i wouldn't say it itches for me, more of a prickling sensation, but i go hilariously bright fire engine red, a real full on flush for sure.

niacin (b3) is an alternative to the statins and the last thing i picked up on about niacin, is that it can elevate serum uric acid levels (which average in the 190 nmol/l range in ms patients and more like 290 nmol/l in healthy controls, still well under the bottom end of the gout range).

initially i started using the flush to get a rush of blood to areas that don't usually get that much, hopefully to deliver more nutrients to areas that need them.

thx for the reply harry , i didn't have any luck with ldn either i took it for 8 months or so. i take codeine for the pain in my legs.

The "itching" with the flush only occured the first 1 or 2 times. Now I only get the plesant flush. However now, if a few hours after the flush I take a hot shower, I get itching alone like you would not believe for about 15 minutes.

It takes about 1200mg of niacin to cause a flush in me now; originally I got it with about 300mg.

Just to be clear, it was with the niacin I had the skin reaction. I only got skin reactions with prokarin when I left the patch on way to long (and I guess the bandage loosened), or as you say, I didnt make an air tight seal.

wow 1200! yea i'm still in the 300 department! that's interesting about the shower itch. good to be forewarned.