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Pathogenesis. The hookworm and an American hookworm are localised in a thin intestine, mainly in duodenal and lean intestines. Larvas of hookworms get to an organism of the master mainly through a mouth and educe in an intestine without migration. American hookworm larvas usually take root activly through a skin, inpour into vascular capillars, migrate on the big and small circles of a circulation. Having reached lungs, through pneumatic pathes, a larynx and a pharynx they get to an esophagus and an intestine where in 4-5 weeks educe in adults of helminths. Parasitizing in an intestine, helminths eat basically blood, putting to an intestine mucosa fine wounds by chitinous arms of a stomatic capsule. In head and cervical parts there are glands which excrete the special anticoagulants which cause a long bleeding. The intensive invasion, especially at children's and young age, can lead to a delay in physical and mental development, to attrition and a cachexia. Quite often in these cases the invasion comes to an end with a lethal outcome. Lifetime of helminths, possibly, 3-5 years, probably, more longly. The majority of Ancylostoma perishes in 1-2 years after penetration into a body of the human.