My concern, however, is using them on MS patients because so little is known about the side effects and possible severe results.
I'll take that when it comes. I'll also take the treatments that reverse "reverseable" disability.
A problem with these sorts of threads is that the "researchers are useless / drugs companies are greedy" brigade can put forward a case against all the current licenced treatments / treatments in trial (interferons / mono-clonal antibodies etc). But where does it leave us with the disease? No treatments!
Thank you for changing the subject Ian and I'm glad that you have opened up the topic of my little pets. As a sensible person that is where you were going with this isn't it......the new and improved Hygiene Hypothesis?bromley wrote:It's alarming to read that MS is increasing in Canada and Europe (in women) and that the increase cannot be just because of better / earlier diagnosis. Attached is an article about another disease (diabetes) which is on the rise. Again, there seems to be an environmental agent at play - another article I read on this story suggested a virus as the trigger / cause which perhaps people are exposed to at a different age.
Yup, just read it.... For a Limey you're A-OK Ian!Another possibility is that children are being exposed to fewer germs, affecting the development of their immune systems.
A really simple, obviously too simple, explanation for relapsing/remitting might involve...
Hi robbie,robbie wrote: we are in two different places with ms maybe when u get to where i am i won't be so annoying to u..but u won't get there right!! i will say it again good luck to u. to me your not a hero your just someone who is grasping at straws..
Ha! Despite my poor memory, I did remember that.lyndacarol wrote:Lyon, because I am the "insulin girl," remember?
As you can see, another effect of Campath is that I am now very polite to slightly annoying middle-age Canadian men. Brock is next on my list for chocolates, but I'd be happy to forward you a box if you PM me with your address.
bromley wrote:... the first therapies for MS have not been as effective as hoped - in terms of stopping / radically slowing down the progression of the disease.
bromley wrote:And with PML, a more vicious demyelinating disease, the JC virus (dormant in the majority of people) is reactivated and the reason for the devastating damage. I don't think PML is described as auto-immune, but it is clear that the immune system does the damage in its efforts to control / clear the virus.
bromley wrote:Campath is very effective at whacking the T cells and B cells, thereby dramatically reducing relapses and allowing the body to repair "reversible" damage, but may also promote some repair
bromley wrote:It is the B cells that are dramatically reduced by Rituxan. This is one of the few drugs that is being trialled for PP MS - where inflammation plays much less of a role (compared with RR).
bromley wrote:Do nothing or do something risky? Those of us with the disease are caught between a rock and a hard place.
HarryZ wrote:I think this thread has been very interesting with many different thoughts and opinions....and no real answers....sounds like MS!!!
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