The following link to a PubMed abstract contains the usual impenetrable jargon. Here is my attempt at translation:
Two of the amino acids on a ligand, (docking molecule), of myelin basic protein are in the wrong position. They are necessary to bind with receptors on the surface of T-cells so that the myelin is not mistaken as "foreign".
Because they do not engage correctly with the T-cell, the myelin basic protein is misrecognised.
Here is the abstract:
tinyURL
Dom.
How myelin gets mistaken
- TwistedHelix
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- TwistedHelix
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- Posts: 602
- Joined: Fri Mar 25, 2005 3:00 pm
- Location: Northamptonshire, England.
Thanks Daisy,
I usually try and fumble my way through the jargon to see if I can extract some meaning from these abstracts, but I'm not a scientist, so don't always take my word for it! I always half-expect someone to reply with a post pointing out that I've got everything wrong!
In this particular extract it looks as if they found a reason, (hopefully "the" reason), why T cells mistake myelin for foreign tissue. If so, this could be an important step forward,
Dom.
I usually try and fumble my way through the jargon to see if I can extract some meaning from these abstracts, but I'm not a scientist, so don't always take my word for it! I always half-expect someone to reply with a post pointing out that I've got everything wrong!
In this particular extract it looks as if they found a reason, (hopefully "the" reason), why T cells mistake myelin for foreign tissue. If so, this could be an important step forward,
Dom.
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