A variation on Ernest Rutherford's dictum is famously known as Occam's Razor, a misspelled attribution to the fourteenth-century English logician and monk William of Ockham. This principle suggests that the simplest explanation for any given problem is usually best. Today, Occam's Razor appears to have been relegated to the dumpster by the bizarre models of quantum physics.
ANY modification of the immune system should be wildly effective? That's far too vague and inaccurate.lyndacarol wrote:And drugs that modify the immune system should be wildly effective!
Another membership into the few and proud Flat Earth Society eh? Tovaxin removes only the myelin reactive T cells and seems to show good results. Campath 1h and High Dose Cyclophosphamide reputedly eliminate the entire immune system and allows a healthy one to grow back and seems to show good results. We have at least two members of this forum on Campath 1H who haven't experienced progression since. No one can say those results will last forever but even a temporary profound result conclusively proves that autoimmunity is involved in the MS process.lyndacarol wrote:Just put me in the camp with those who believe that MS is not an autoimmune disease.
I feel I need to clarify my words: I do believe the immune system is involved in the MS cascade (I happen to think that excess insulin starts the process.). I do not think the disease is autoimmune. As someone at this site once wrote: Would the body wake up one day and attack itself for no reason; then remit; then attack again?even a temporary profound result conclusively proves that autoimmunity is involved in the MS process.
two members of this forum on Campath 1H who haven't experienced progression
For 14 of these volunteers, the progress of their disease initially appeared to be completely halted. In the remaining 13, however, their MS symptoms continued to worsen even in the absence of new inflammatory lesions. MRI studies have discovered that the trial subjects, whose disease continued to progress, were the ones that had the greatest amount of existing lesions and brain atrophy. Unfortunately, as time goes on, it appears that even some of those people whose progression appeared to have been arrested by the drug are now beginning to deteriorate as well. These results have led Campath's researchers to make several important inferences:
Hi Lynda,lyndacarol wrote:Lyon--I love your fireworks animation!!!
I used to think that was a sensible and obvious argument but several times recently Tim Wesner has stated that everyone produces myelin reactive (read that "attacking") T cells and the difference between those with MS and those without is that the systems of those without MS keep the number of those mrtc's under control. I don't know his source for that information but Tim has inside information with Opexa researchers and those researchers likely are in a position to make that determination.lyndacarol wrote: Would the body wake up one day and attack itself for no reason; then remit; then attack again?
Hi robbie,robbie wrote:Bob how many people are on Campath,? and does it have 100% sucess rate like Tovaxin, seems like these are the only two things that boast these kind of numbers.
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