McAlpine's 4th edition

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McAlpine's 4th edition

Postby Lyon » Wed Sep 19, 2007 1:49 pm

I thought some of you might find Section 3, chapter 8, heading "THE SPECTRUM OF DISORDERS MIMICKING MULTIPLE SCLEROSIS", subheading "DISEASES THAT MAY CAUSE MULTIPLE LESIONS OF THE CENTRAL NERVOUS SYSTEM AND ALSO OFTEN FOLLOW A RELAPSING-REMITTING COURSE" written by David Miller and Alastair Compston.

Of course the book goes into details of the diseases but I have to type all this so I'm just giving the disease names.


PLEASE KEEP IN MIND THAT WHAT LIKELY IS EVEN MORE IMPORTANT IS THE INFORMATION I DIDN'T INCLUDE AND WHICH OFTEN INCLUDES REASONING WHY THESE DISEASES CURRENTLY WOULDN'T BE MISTAKEN FOR MS

Acute disseminated encephalomyelitis

Acute haemorrhagic encephalomyelitis

Systemic lupus erythematosus

Anti-phospholipid antibody syndrome

Primary Sjorgren's syndrome

Behcet's disease

Central nervous system vasculitis

Systemic vasculitis with central nervous system involvement

Isolated central nervous system vasculitis

Systemic sclerosis

Susac syndrome

Noninflammatory cerebrovascular disease

Cerebral autosomal dominant arteriopathy with subcortical infarcts and leucoencephalopathy (CADASIL)

Sarcoidosis

INFECTIONS:
Lyme borreliosis

Meningovascular syphilis

Human immunodeficiency virus (HIV)

Progressive multifocal leucoencephalopathy

Subacute sclerosing panencephalitis

Whipple's disease

Primary lymphoma of the central nervous system

Mitochondrial disease

SYSTEMATIZED CENTRAL NERVOUS SYSTEM DISEASES
Hereditary ataxias and paraplegias

Leucodystrophies

Adrenoleucodystrophy

Metachromatic leucodystrophy

Globoid cell leucodystrophy (Krabbe's disease)

Adult onset dominant leucodystrophy

Vanishing white matter disease

Hereditary adult onset Alexander's disease

Oculodentodigital dysplasia syndrome

Vitamin B12 deficiency

Myelopathy due to nitrous oxid toxicity

Cerebrotendinous xanthomatosis

Leucoencephalopathy related to glue-sniffing

Multiple system atrophy

Paraneoplastic syndromes

Coeliac disease

Myeloneuropathy from acquired copper deficiency

Cerebellar ataxia with anti-glutamic acid dhydrogenase antibodies

Motor neuron disease and its variants

ISOLATED OR MONOSYMPTOMATIC CENTRAL NERVOUS SYSTEM SYNDROMES
Structural and noninflammatory infectious spinal cord syndromes

Spinal cord compression

Cervical spondylotic myelopathy

Chiari malformation

Spinal dural arteriovenous malformation

Tropical spastic paraplegia: HTLV-1--associated myelopathy

Noncompressive progressive myelopathy

Acute spinal cord compression

Spinal cord stroke

Transverse myelitis

Acute necrotizing myelitis

Other forms of myelitis

VISUAL FAILURE There are innumerable infective, toxic or physical causes of optic nerve disease that are unlikely to be confused with multiple sclerosis. Several rare causes due to systemic disease resulting in diagnostic difficulty have already been discussed above under a number of headings.

Anterior ischaemic optic neuropathy

Lever's hereditary optic neuropathy

Central serous choroidoretinopathy

Neuroretinitis

Chronic relapsing inflammatory optic neuropathy (CRION)

Paraneoplastic optic neuritis

Progressive visual failure

Sensory symptoms
Central pontine myelinolysis
Lyon
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