Yea..........I really can't say personally one way or the other whether antibiotics work for MS or not. My position is usually one of just being questioning. Hey........I'm all for anybody taking whatever works for them, ya know? The only personal opinion you may see me take in a more decisive manner is that MS itself may actually encompass more than one "type" of disease (I refer a lot to Dr. Claudia Lucchinetti's ongoing research.) Hence, also why it may be entirely possible that antibiotic treatment may indeed work for many! I myself have a drug treatment option that I would love to see investigated and put into clinical trial, too.
And that's the problem that tends to show itself time and again. There may be, and probably ARE, many different MS therapy options, such as LDN, minocycline, etc., that are basically being ignored and/or patients have a lot of trouble getting prescriptions for. That principle, to me, is unfair in and of itself (i.e. denying someone the option of trying something simply because it may not be popular or backed by the pharma companies).
The thing is, though, too..........and again, this is one of my "wondering aloud" things............Chlamydia pneumoniae and minocycline seem to be lumped together quite often, which I'm not certain that they should be.
If Chlamydia is found to be an aggravation in MS, the treatment may not always need to be antibiotic treatment. If you can stop the overload influx of CA2 (calcium) into a neuron, that also helps to prevent disability and damage to myelin in MS. The chlamydia pathogen is coincidentally also stopped from causing further damage, if you can control the influx of CA2. There are other drugs besides antibiotics that can do that.
Now, as far as minocycline goes, I found that one of the major things minocycline does that helps MS is not one of stopping bacterial infection, but is its ability for decreasing the activation of caspase 3. Caspase 3 is part of the physiological chain reaction that activates apoptosis, i.e. cell death (and is not directly connected to its antibiotic efficacy). If you can regulate the activation of caspase 3, it helps to control cell death (which as we all know, in MS, it is desirable to stop, slow down, or at least regulate apoptosis).
So....the one does not always need to be linked with the other, but it can be and often is.
Dr. Sriram's research is mainly regarding chlamydia as a possible cause of MS, not regarding the efficacy of minocycline necessarily. Minocycline as a drug therapy is also being looked at by itself, not necessarily connected with the fact of whether you have the chlamydia pathogen.
Bottom line? Is it possible then that minocycline (and/or other antibiotics) might be effective adjuncts for MS therapy? Certainly! And as we all know, especially the folks who are supportive of LDN, how difficult it is to get it proven, so patients can at least have the option of trying it!?
I support the freedom of patients to try viable alternative options of treatment, especially when it is being done in an informed manner, and is under the supervision of medical personnel. Now to get the medical doctors to get on board with us!
EDIT: Wait a minute! I said above that the "only" decisive personal opinion you may see me take, blah blah!!! Geez, who am I kidding!? (Especially for those of you who know me. hehehe..........
SECOND EDIT: Sorry, I changed the word "virus" to "pathogen". I misspoke by using the term virus. Apologies.