also believe that the amount of pseudo science and layman theories around it is one reason why most researchers don't want to study LDN, and I'd hate to see the same thing happen to minocycline. It is not a miracle drug, but it seems to be too good to be wasted.
The internet, of course, is filled with tons of junk and the many theories that exist about the cause of MS is part of it. But researchers of any quality know the difference between fact and fiction.
I believe the main reason that LDN isn't part of any major research as yet has everything to do with financial reasons and not with anything that is posted on the internet. There are some individual neuros who are looking at pilot LDN trials and the Consortium who are looking at something a bit larger. Dr. Bihari, owning the utility patent on LDN, also can inhibit any large interest in this drug because he can have a final say in the research as it applies to MS.
Add to this the influence of the CRAB pharmas (especially on the NMSS) and you can see why very little has happened to date when it comes to LDN trials.
I know how the NMSS can torpedo anything they don't agree with when it comes to MS research and as we all know, they have initially torpedoed LDN with their infamous press release.
Hopefully, over time, science will win out over finance but we know what a terribly slow process that can be.