Well, I must say that I don’t know any neuros in the LA area but I’d agree with the recommendations you’ve already received to go with Giesser. She seems like an excellent choice to me since it appears she’s involved in the research on hormones and MS at UCLA, including the pilot trial of testosterone
I’m definitely biased towards the view that all people with MS should have normal hormone levels (cortisol, DHEA, estrogen, progesterone, testosterone) and it’s just possible given her interests in hormones that she might be willing to test your hormone levels and be certain yours are all in the normal range and prescribe accordingly if they're not.
Just to whet your appetite (for normal hormone levels, sorry there’s no cheese here) here’s a link to a fairly technical article: Recent Developments in the Significance and Therapeutic Relevance of Neuroactive Steroids
Some relatively understandable quotes from the article:
How can one class of compounds have so many potential applications? The answer may lie in the ability of neuroactive steroids to regulate synaptic and extrasynaptic inhibitory transmission across brain, hypothalamic-pituitary-adrenal (HPA) axis function, inflammatory processes and myelin formation.
Neuroactive steroids modulate CNS development and repair following injury
The neurodevelopmental functions and mechanisms of action of four distinct neurosteroids – pregnenolone, progesterone, allopregnanolone and dehydroepiandrosterone are reviewed by Mellon (this issue). Absence or reduced concentrations of neurosteroids during development and in adults may be associated with neurodevelopmental, psychiatric, or behavioral disorders. Treatment with physiologic or pharmacologic concentrations of these compounds may also promote neurogenesis, neuronal survival, myelination, increased memory, and reduced neurotoxicity.
Progesterone and its metabolites also promote the viability of neurons in the adult brain and spinal cord….Thus, the hormone may promote neuroregeneration by several different actions: by reducing inflammation, swelling and apoptosis, thereby increasing the survival of neurons, and by promoting the formation of new myelin sheaths. Recognition of the important pleiotropic effects of progesterone supports the therapeutic potential for the treatment of brain lesions and other diseases of the nervous system.
Neuroactive steroids modulate the HPA axis and the effects of stressThe ability of neuroactive steroids to reduce HPA axis activation may play an important role in returning the animal to homeostasis following stressful events.
This abstract helps explain why reducing HPA axis activation might be important to people with MS. The role of stress-response systems for the pathogenesis and progression of MS
whereas hyperactivity of the HPA axis has been linked to neurodegeneration and increased disability.
Now back to a final quote from the article:
Summary and Conclusions
….there is great optimism in the field for the usefulness of the inhibitory, anti-inflammatory, and myelin promoting targets of neuroactive steroids for CNS disease.
Maybe Giesser will share the author’s enthusiasm for normal levels of “neuroactive steroids”—obviously I do.
Interesting that the article doesn't mention estrogen--although low levels of estradiol were associated with disability levels in a small study of men with MS.
All the best in finding a neuro who will work for you.