I'm considering a sex change!
I knew it was going to come to this.
Before and after pictures would be nice. Thanks for posting this.
As an FYI for anyone who’s interested, here’s the link to the AAN Conference abstract: Gender Related Differences in Multiple Sclerosis. A Large Cohort Study of Conventional and Non-Conventional MRI Measures
CONCLUSIONS/RELEVANCE: These results suggest regional atrophy differences between male and female MS patients. GM and central atrophy are more advanced in male patients while WM atrophy is more advanced in female patients.
Besides the influence of hormones on atrophy, I wonder if this research is yet another indicator that MS is neurodegenerative. After all, men have thicker myelin than women, yet they have more gray matter atrophy than women. If it all started with the myelin one would think men would have less rather than more gray matter atrophy than women (thicker myelin presumably delaying the ultimate death of neurons/axons) and vice versa, or so it would seem. Quite intriguing.
"I think that we are going to hear more and more about sex influence in MS. Its a totally new, very important chapter."
I’m thrilled with this news and hope they don’t equate or limit research in gender differences simply to the study of sex hormones. Both are welcome though--they’ve been a friggin’ long time coming for a disease that has had a decidedly gender bias for quite some time now. Too bad it‘s been more or less ignored until recently.
Dr. Zivadinov suggests that we might be able to discover whether a sex hormone deficiency plays a role in a particular patient's illness, and do something about it.
Yes! Although I hope they don’t get stuck on just estrogen and testosterone.
As we've now learned, the saliva hormone tests aren't as reliable as the blood tests.
A slight word of caution here--I know that traditional practitioners loathe saliva testing. It’s been my non scientific understanding though that the key concern is to test for “free” hormone levels. Most, but not all, serum tests check for bound hormone levels rather than “free” levels. If it’s bound, it may not be available to the brain, CNS, etc. So, if you have serum testing, I’d be certain to verify that it will provide info re: “free” hormone levels.
Here’s a link to some recent fun non MS research and I was happy to see researchers beginning to use saliva testing.Is estrogen testosterone for women?
Saliva samples were taken to measure their hormone levels.
Really want to suggest testing and bio-identical hormone replacement to all Msers
Totally and enthusiastically agree.
I had an attack during my pregnancy. It lasted from the 2nd month to the last month. I didnt recover until a couple weeks after I delivered.
Sorry you didn’t experience any relief and only aggravation during your pregnancy. It seems certain that not everyone benefits during pregnancy. Lots of factors appear to be involved in MS.
Take care all--I'd love to see research on sex differences and hormones in people with MS get off the ground level. Maybe this research is just the ticket since it was such a large sample of people, not rats.