Advance in understanding programmed cell death

If it's on your mind and it has to do with multiple sclerosis in any way, post it here.

Advance in understanding programmed cell death

Postby dignan » Fri Nov 12, 2004 12:30 pm

This research looks potentially promising.


By impounding iron, FHC foils cell suicide, fuels inflammation
12 Nov 2004

A research team based at the University of Chicago may have found a way to manipulate cell suicide, also known as programmed cell death, a normal process that regulates cell number but that goes awry in chronic inflammatory disorders, cancer and other diseases.

In the 12 Nov. 2004 issue of the journal Cell, the scientists show that a key step in the process of preventing cell suicide is the induction of ferritin heavy chain (FHC), a protein that collects and hoards iron. By sequestering iron -- which cells with suicidal tendencies need to make the harmful substances that induce death -- FHC prevents cellular suicide.

This finding suggests that drugs that modulate FHC or iron metabolism could provide a new and effective approach to anti-inflammatory therapy without the side effects, such as weakening the immune system, that come with current treatments.

http://www.medicalnewstoday.com/medical ... wsid=16267
User avatar
dignan
Family Elder
 
Posts: 1608
Joined: Wed Aug 11, 2004 3:00 pm

Advertisement

Postby Arron » Fri Nov 12, 2004 1:44 pm

Great post! Thanks!
User avatar
Arron
Volunteer Moderator
 
Posts: 892
Joined: Sun Feb 01, 2004 4:00 pm
Location: California, USA


Return to General Discussion

 


  • Related topics
    Replies
    Views
    Last post

Who is online

Users browsing this forum: tzootsi


Contact us | Terms of Service