I personally only have one known trigger for a relapse, so it acts as a predictor me. All cold/flu infections will trigger a relapse within 2 weeks. I also know that 2 single daily doses of oral prednisone of 75mg will stop the relapse (once it has started, I haven't tried taken it before I notice the relapse).italianphil wrote:do you know if there's anything, a test or something that could predict a relapse in order to take action as soon as possible?
italianphil wrote:I am working on Dendritic Cells and Microglia and my focus is on TLR signal transduction pathways. I am interested in the role of these cells in autoimmunity. These cells are involved in the demyelination process and would like to understand whether clinicians already know of any interleukin, interferon, produced by these cells BEFORE the relapse that may be interesting to study relapses in EAE animal models. Using the EAE model, researchers at UPENN were able to prevent relapses by treating the mice with anti-IL12 antibodies. Dendritic cells are key producers of IL12 and they are the controllers of Tcells and probably provide "wrong" signals to them. I want to know more about these signals. CureOrBust post is very interesting because he can predict relapses with a flu, well Dendritic cells are among the very first cells that react to the virus and that eventually trigger the immune response.
Please continue letting me know whether you know of any particular test that can predict relapses.
Ok, there is one other circumstance that can "trigger" a relapse. More the case of "induce". I tried the antibiotics protocol against MS (roxy, doxy & pulsed flagyl). I found that five days of flagyl could trigger a "relapse". Those on the protocol would attribute this to a "pseudo relapse" (caused by bacterial die-off, i.e. herxheimer reactions), but I feel mine were real.italianphil wrote:CureOrBust post is very interesting because he can predict relapses with a flu, well Dendritic cells are among the very first cells that react to the virus and that eventually trigger the immune response.
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