Hey, was that an old f@rt crack?cheerleader wrote:Wanted to bump this thread 'cause I have some questions for the elders.
I take 75mg/day for 3 days, with NO taper. I found the lower doses were nowhere near as effective, and it was only the high days that made a difference; so cut the taper. I think IV works on the same basis; ie a short HIGH dose. I talked to my docs at the time, and they were both comfortable with up to 7 days at 75mg without a taper; I only do three to be extra safe.cheerleader wrote:He took 60mg. for 2 days this weekend, and felt terrific...his first days with no pain at all since his dx. He's been feeling great and is now on the taper down to 20mg. He'll be done in a couple of days.
I have never done IV steroids, so who knows how good it would be for me; I am pretty satisfied that the 75mg/day does about all it can. At the time, I was told 1mg/kg body weight, which would be 70mg, but three tablets of 25mg are just too easy to take. There was a discussion about the dosages on here somewhere, and we found some ludicrously high recommendations for other conditions.cheerleader wrote:He had IV solumedrol at his first flare 2 years ago. The neuro thought it wouldn't work for him, since he'd had symptoms for over a month before starting steroids...yet he had immediate relief from pain and a return of function.
Ahh.. I think you might like this thread (http://www.thisisms.com/ftopicp-23620.html), it has your pet subject in mind. It was just over 2y ago, before you joined, and it has links to articles that show that steroids shut down the leaky BBB, so as far as I could find, no one has proved conclusively if they work in MS because of the inflammation, the immune-modulation, the shut-down of the BBB (ie the endothelial), or a combination of all three.cheerleader wrote:My question is....if prednisone is so successful in relieving his pain, would this mean that inflammation is at the root of his leg pains? His blood tests always show inflammation.
J Am Diet Assoc. 1984 Feb;84(2):157-63.
Zinc status of asthmatic, prednisone-treated asthmatic, and non-asthmatic children.
Goldey DH, Mansmann HC Jr, Rasmussen AI.
To assess interrelationships between asthma, corticosteroid therapy, growth, and zinc status in children, measurements of height, zinc and copper in serum and hair, taste acuity, and dietary intakes of energy, protein, zinc,and copper were analyzed for 29 asthmatic, 11 prednisone-treated asthmatic, and 21 non-asthmatic subjects, 6 to 20 years old. Reduced height attainment was significant only for the prednisone-treated asthmatic group and was not correlated with clinical or dietary indexes of zinc status. Dietary intake data were similar for all three groups; in comparison with the RDAs, daily intakes were adequate for both energy and zinc (80% to 90%), high for protein (185% to 225%), and low for copper (35% to 60%). Results confirmed earlier reports of growth retardation in corticosteroid-treated asthmatics; significant indications that reduced food intake or impaired zinc status played a major part were not evident.
...are you taking some zinc?
msmything wrote:My question is...is there blood work that can detect when your adrenal glands start to kick in making their own corticosteroid? The wean process is slow and long. it's supposed to take 6 mos to get down the last 4 mgs.
How do you tell if your bady is responding, or if you're going to fast.
Lack of corticosteroids in the blood may cause the pituitary gland to produce more corticotropin hormones to stimulate the adrenal glands. Since corticotrophin affects melanin production, excess levels of corticotropins may cause dark pigmentation of the skin and lining of the mouth.
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