it is a complicated syndrome involving a number of problems and co factors, mainly bacterial and also viral overgrowth in an otherwise susceptible person. 'Susceptible' is clearly partly genetics, possibly stress and it appears some nutritional factors (like vitamin d) that all come together in a perfect storm to produce what we call MS in an individual.
There is some interesting further reading on this link:
And one idea which especially intrigues me is that fibrin deposits provide a good hiding place for viruses or bacteria, both from the immune system and drug therapies. Therefore the idea is to begin removing the fibrin first to expose the pathogen, before administering antiviral or antibiotic drugs. If there are enough deposits for the pathogen to hide in, the suggestion is that it may enter a dormant state and only become active again when the fibrin is removed and it becomes vulnerable.
I wonder if this roller-coaster provides a believable scenario for a relapsing remitting disease course? Infection leads to fibrin deposits; enough fibrin leads to dormancy, fibrin removal leads to pathogen reactivation; reactivation leads to more deposits.
Fibrin has come up in the past as a therapeutic target in MS.
I have spent far too much of my life laying on the floor waiting for an ambulance to come, having fallen and sometimes injured myself. I've lost count of the number of times they praised my blood for being so sticky: perhaps not such a good thing after all,