Depression was Jeff's presenting symptom, some 15 years ago. He waited many years to take an antidepressant. Of course, now seeing his MRIs, we understand. Most of his lesions are in the corpus callosum, the part of the brain which connects emotion and language. Hard to talk about how you feel when your brain is being disrupted. Effexor helped him function.
I believe he suffered from a form of "vascular depression" found in the elderly with circulation issues. Depression is often the first sign of neurological illness. He's been so much better with improved circulation, nutrition, exercise, supplements and understanding he has MS....but he'll probably be on Effexor the rest of his life.
hope you find your own answers...
Husband dx RRMS 3/07
dx dual jugular vein stenosis (CCSVI) 4/09