Cochrane Group stud was highlsuspect at best if it is critically examined. I do not contend that Copaxone is a great med, good first line. It IS excepted within the neuro community that all the injectables offer about 30% give or take a few points. and the difference boils down to s/e's.
Copaxone's competitors contend that it is not a very good medication either. Then again, in the marketing war of MS pharma, one has to take those comments for what they are. But the Cochrane Group is an independent group of scientists who have no vested interest in these drugs and simply relate what they find. I have a tendency to believe them a lot more. As for the so-called 30% efficacy of the CRABs....even if one believes that number it is quite lousy for very expensive drugs that give you many bad side effects!
The problem with most neurologists is that they really do not think out of the box in terms treating the underlying immune proce ss. Fearing the documented 1/3000 risk of Tysabri which is probably drastically overstated opting to keep patients on the medications mentioned.
I won't disagree with your comment on the neuros not thinking outside the box. Because they have been in this "box" for so many years both in research and treatment, look where we are today in respect to advances in MS treatments. Why does the word "abysmal" keep on coming to my mind on this one?
Tysabri....I won't comment on that drug....most people on this forum know of my concern for this medication. I'm afraid we've only seen the tip of the iceberg of the problems that his drug is going to cause.
I also half agree with the uselessness of MR scaning is only as good as the scanner itself and the radiologists and a techs performing the tests.
How many people have had 3 tesla scanning done?
Probably not very many...likely because of the availability and cost.