Harry Z is on the right track, and I have a little proof to throw out.
...the number of brain lesions do not equal the number of attacks. What really counts is where the lesions are forming. You can have several lesions and no symptom change or just a couple of lesions and major symptom increase. The biggest problem with MRIs and the lesions that they show is that there isn't a correlation between the two. Most clinical studies spend a lot of effort taking MRI's to see how the drug may be doing but they all say the same thing.....no corrleation between the two so it's impossible to know solely by an MRI if the drug is working or not.
I posess clinical evidence that suggests that there is ABSOLUTELY
no correlation between lesions and attacks. The two MRIs I've had over the past two years have shown a progressive reduction in lesions. Over this time period, I quit taking Avonex after six years, I am taking none of the FDA "approved" terapies, and my physical vitals (blood pressure, blood profile, etc.) have improved. Basically, I am a more healthy person.
What this suggests is that an MRI shows nothing, and the ABCR drugs may be harmful. It DOES NOT show if a drug is working or not! If someone claims that they do, question where this person got his/her evidence. Please always question those in your employ (your doctors). They should be dedicated to improving your physical well-being and communicating with you how his/her treatment options will do this. As patients, we need to communicate to doctors that the medical industry is WAY OFF base in its approach to treating people who suffer from MS. Thus, we need to always question what, and why, is his/her approach to treating me.
If a doctor is going to treat me for something, s/he had better be 100% certain that the treatment improves my overall health. No treatment that has been prescribed to treat MS does not meet this criteria.
However, if you are certain that the ABCR drugs work, then they do, but you should challenge your doctor to help make you well with healthful diet and exercise prescription. If you want to get well, stay simple: eat better and exercise more! It is a sure way to improve health. I dare you to find a doctor who disagrees.[/code]