But still the answer is yes, ms is a thing that has no predictive course, you know, evth is possible, spontaneous remissions are well-known and can last for tens of years. If you're lucky.
They hope it is the drug. But, AFAIK, a few decades ago, when there were no drugs available, others felt better with time, others worse, others much worse. The same happens today, despite the DMDs.
A total of 1562 patients (85 percent) had relapsing–remitting disease initially, whereas 282 patients (15 percent) had progressive disease. In the entire group of 1844 patients, the median time from the onset of multiple sclerosis to the assignment of a score of 4 on the Kurtzke Disability Status Scale was 8.4 years (95 percent confidence interval, 7.8 to 9.6). The median time from onset of multiple sclerosis to the assignment of a score of 6 was 20.1 years (95 percent confidence interval, 18.1 to 22.5), and the median time from the onset of disease to the assignment of a score of 7 was 29.9 years (95 percent confidence interval, 25.1 to 34.5). The median interval from the onset of disease to the assignment of each of these scores was significantly longer (P<0.001 for each comparison) in the group of patients with a relapsing–remitting onset of disease than among those who had progressive disease at onset (Table 2 and Figure 2).
The objective of this study was to determine the influence of acute relapses on the rate of progression of irreversible disability in patients with multiple sclerosis.
Conclusions Among patients with multiple sclerosis, relapses do not significantly influence the progression of irreversible disability. (N Engl J Med 2000; 343:1430-8.)
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