McDonald criteria & Differtial Diagnosis

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McDonald criteria & Differtial Diagnosis

Postby CureOrBust » Mon Feb 16, 2009 5:24 am

I have recently been noticing that a lot of published papers talk of participants being included via the McDonald criteria, which is considered the "gold standard" for diagnosing MS. So I went and brushed up on exactly what the meant.

Looking at the McDonald criteria, there is no reference to testing for differential diagnosis. :?

Does that mean that these studies could be including people who have only met the McDonald criteria and have not had any tests to exclude a differential diagnosis that would present and satisfy the McDonald criteria?
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Postby jimmylegs » Mon Feb 16, 2009 6:44 am

is mcdonald the one that has that bit about 'lack of any other explanation'? i think that's what they mean by doing differential dx stuff but i haven't looked into it in a while...
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Postby CureOrBust » Mon Feb 16, 2009 8:30 am

I found the fulltext, I will read it tomorrow. :oops:
http://www3.interscience.wiley.com/cgi-bin/fulltext/112140800/PDFSTART

I did a quick scan and it appears to say "if nothing better explains the presentation, then it is MS".

If that's as far as it goes, it's a little loose for my likings, as it depends on the person making the diagnosis, and how thorough they feel is appropriate. But, I will read and see.
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Postby jimmylegs » Mon Feb 16, 2009 9:06 am

it's VERY loose. so are the rest of the criteria in my opinion.
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