Viagra helped me the first time I took it, then never again. Then we started the regiments of Cialis, penile injections, ect.... The injections work, however, that is a DEFINATE mood killer when you have to say to your spouse, "hang on sweetheart, let me give my johnson a shot".. and it is VERY uncomfortable. I eventually ended up getting a penile implant. I had my first one (yes, first one) as well as my second, third, and forth one prior to me knowing about my MS. They couldnt figure out why my body kept rejecting my implants. Now we know why. Thank God, my last one took well and its been in for two years with no problems. All that being said... Now that I have one like and 18 year old, I dont want to use it. Sounds crazy I know. It has caused major problems between me and the wifey. But I was wondering if it is the MS that is causing the lack of desire? I mean, I would rather drink beer and watch the grass grow as opposed to use it. I dunno. Now the doc has me on testosterone cream, but I constantly forget to use it. So, I really cant say if it works or not. I wish I had desire, believe me, it would make my life a whole lot better, and the wifey would be happy. Now I put all my dirty laundry out here, I hope someone has some suggestions. I only posted this info because I know what you are going thru.