HarryZ wrote:Don't get too hung up on lesions. They come and go, healthy people have them and there isn't correlation between lesions and symptoms.
I completely agree with Harry's comment above. I'll also add that the brain is very plastic, continually able to form new neural pathways around damage, while the limited space in the spine makes it less forgiving of lesions - and maybe harder to spot them.
Here's a link to one of my favorite sites - The Whole Brain Atlas. If you scroll down to the MS section you can take a "tour" of an MS brain. If you click on "Cine" you can see time-lapse MRIs, and watch lesions both come and go in only weeks and months. You can even choose the "slice" or section you want to view.
And...they know that many lesions aren't easy to spot even though they're there. You get different results according to the equipment and the skill of the MRI film reader. In my case, my brain was so full of classic MS lesions that I got an "instant" dx after a single MRI (of brain & C-Spine) without contrast, and before I went to a single neuro. Later docs noted them in my brainstem, C-spine and optic nerve, but those weren't mentioned in the original report. I think I have a relatively mildish case of MS, maybe because I've had it so long I've managed to slowly adapt to it all. And my brain is loaded
Harry, that's very interesting info about your wife's lesions. I was so sorry to hear of her death. It's too bad that they don't order as many MRIs of the spine as they do of the brain. As I'm still sloooowly progressing, I think I might request a spinal MRI at my next neuro visit and see what happens.
Good health and good thoughts to all!