VailKin wrote:Could someone please help me answer this question? Do the CRABs really influence the course of MS? I'm currently on Avonex (1+ years) and am questioning it. Do I want to be injecting myself full of this stuff if it really only slows progression in 30% of people using it? How far from being statistically insignificant is that 30% and is that 30% real-life results or clinical malarky?
Are there any non-pharmaceutical funded studies that point to the effectiveness of this stuff? Show me the way, please?
Thank you and Happy New Year!
dxd 1994 Climb on!
If you ask most MS docs about the CRABs, they will tell you publicly that you should take one of them to try and slow down the progression of the disease.
If you get them to comment privately (and most won't) they will likely tell you that they are very disappointed in the results. What the drug manufacturers told them about these medications in the beginning vs the real results are two very different scenarios.
I can remember some of the comments that were made about the CRABs when Tysabri first appeared with its once every 4 week infusion. These docs made a lot of less than complimentary comments about the CRABs. They were glad that their patients would have the chance to rid themselves of the more often than not bad side effects of drugs that did little to alter the course of the MS.
Now that Tysabri's long term safety use has come into question, these docs now have had to strongly consider putting their patients back on one of the CRABs.
Pretty much sums up the state of trying to treat MS these days.