Aha! I finally figured it out. I've been trying to remember which of these new meds had mentioned macular edema (swelling on the retina) as a side effect, and it's fingolimod. And it caused lots of skin cancer too – both of them conditions I've had problems with in the past. Here's an older article.
Macular edema had been seen with fingolimod in previous transplantation trials, and there were 4 cases of suspected macular edema in this trial (1 since the month-24 analysis). However, the diagnosis was not confirmed by external review of retinal specialists. There was some elevation of hepatic enzymes, but as had been seen with other adverse events, the frequency declined over time, Dr. Comi noted.
"All of these data taken together continue to suggest that the drug is active; second, the frequency of adverse effects tends to decrease with continuation of the treatment, and there was no evidence of any new adverse effects except some reports of skin malignancies," he said.
Seven cases of skin malignancies were observed during the extension trial: 3 basal-cell carcinomas, 2 squamous-cell carcinomas, and 2 melanomas. All were in situ, and all have been treated without other complications, he said.
They've never found evidence of optic neuritis at my ophtho exams, but I've been told I currently have dry eye syndrome, early stage cataracts, I got my first ever ocular migraine last summer (pretty cool psychedelic vision
), and a touch of nystagmus (my ONLY eye issue that's related to MS).
And that's why I pay so little attention to new meds. I already have enough medical problems without giving myself new ones on purpose. And my MRIs have never shown enhancing lesions anyway.