Thanks dignan that like was interesting that p53 seemed to affect microglial behaviour.
Yes Harry I've read an abstract on research on how p53 affects tanning. This is for p53 proteins that are functioning normally and was probably researched as it was a newly discovered function of p53. Traditionally they're main role was viewed as checking cells as they developed and killing them if there was a fault. A more detailed and accurate definition is at wikipedia.
Also notasperfectasyou thanks for the article.
Since I read that p53 is up regulated in MSers I've been trying to find out if there has been studies to see if the tp53 gene or the p53 protein of MSers are modified in some way. I know that HPV binds an E6 protein to p53 which inactivates it. What I've wondered is could p53 be changed to increase cell apoptosis.