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Cardiovascular effects of oral MS drug Gilenya transient

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squiffy2

Post subject: Cardiovascular effects of oral MS drug Gilenya transient

Posted: Thu May 19, 2011 3:17 am

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Joined: Wed Oct 14, 2009 3:00 pm
Posts: 1711

Cardiovascular effects of oral MS drug Gilenya mostly transient

The first approved oral medication for multiple sclerosis causes transient reductions in heart rate and atrioventricular conduction and a sustained increase in blood pressure, according to investigators who analyzed pooled data from two phase III trials.

The cohorts from the two phase III clinical trials of fingolimod (Gilenya) for relapsing-remitting muscular sclerosis involved 854 patients treated with the currently approved dosage offingolimod (0.5 mg/day), 849 patients on a higher dosage (1.25 mg/day), 418 patients on placebo, and 431 patients treated with weekly intramuscular injections of 30 mcg interferon beta-1a (Avonex) for 1-2 years.... Read More - http://www.msrc.co.uk/index.cfm/fuseact ... ageid/1309

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Board index » Treatments » Gilenya

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Topics		Author	Replies	Views	Last post
Related topics
	First oral MS drug, Gilenya, now available in UK	squiffy2	0	1032	Mon Apr 18, 2011 11:51 pm squiffy2
	Reducing the side effects of MS drug, Gilenya	squiffy2	0	1357	Tue May 10, 2011 1:28 am squiffy2
	Deaths hit oral MS drug, Gilenya	squiffy2	0	1469	Tue Mar 06, 2012 11:42 pm squiffy2
	SMC turns down oral MS drug Gilenya	squiffy2	0	1214	Tue Mar 13, 2012 12:59 am squiffy2
	New MS oral drug, Gilenya, still not available in Eire	squiffy2	0	1138	Tue May 08, 2012 1:56 am squiffy2

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