Actual details on reduced Lymphocytes count?

Gilenya, or Fingolimod, is the first approved oral disease modifying drug for MS.

Actual details on reduced Lymphocytes count?

Postby CureOrBust » Sun Dec 04, 2011 3:32 am

I tried doing a search to find the actual numeric effects on cell counts of circulating Lymphocytes before and after being on Gilenya. I didn't find it. The best I found was an approximation for mice in an experiment, who I would assume would of been on much more severe doses.

I would love to see the data from the Phase II and Phase III trials; which used different dosages? Is this data available anywhere?

Even better would be a graph plotting treatment response (eg EDSS) to Lymphocyte reductions, if there is any pattern to the response.
User avatar
CureOrBust
Family Elder
 
Posts: 2900
Joined: Wed Jul 27, 2005 3:00 pm
Location: Sydney, Australia

Re: Actual details on reduced Lymphocytes count?

Postby Shayk » Sun Dec 04, 2011 7:52 pm

Hi Cure

I don't have a clue if the info you want is in these documents but this is a link to info
on the FDA website about Gilenya.

Take care

Sharon
User avatar
Shayk
Family Elder
 
Posts: 777
Joined: Fri Feb 06, 2004 4:00 pm

Re: Actual details on reduced Lymphocytes count?

Postby CureOrBust » Mon Dec 05, 2011 2:54 am

I did a quick skim read, and it appears to be a wealth of info. Thanks. :-BD
User avatar
CureOrBust
Family Elder
 
Posts: 2900
Joined: Wed Jul 27, 2005 3:00 pm
Location: Sydney, Australia

Re: Actual details on reduced Lymphocytes count?

Postby lmacalus » Mon Dec 19, 2011 12:27 pm

Have you tried calling Novartis & asking them? Could it be contained in the PI?
User avatar
lmacalus
Family Member
 
Posts: 65
Joined: Sun Apr 05, 2009 3:00 pm


Return to Gilenya

 


  • Related topics
    Replies
    Views
    Last post

Who is online

Users browsing this forum: No registered users


Contact us | Terms of Service