I'm in the US (California) and started in the Phase III study of ocrelizumab vs Rebif.
I had my first dose (well half a dose) on Wednesday. I ran a low grade fever started 40minutes into the infusion.
I had my first "rebif" shot on Wednesday after the infusion. I take my second shot today. I really hope the rebif is placebo.
I feel like the moment of truth is approaching…maybe. In a little while, I will inject myself with either a placebo or the rebif….if I get side effects, then I know that the infusion I had the other day was saline and no miracle cure. If I don’t have any side effects - it doesn’t actually mean anything, b/c the shot is being titrated up to full dose, so it’s a fraction of a dose, so it may be too low to trigger side effects yet. I HATE NOT KNOWING. But in my mind, I want to be delusional and say that if I don’t have any side effects, it means I’m getting the REAL med in the infusions and these “Shots” 3x a week are placebo. Other thought is to make my partner “taste” what is in the syringe…and if it tastes like saline, we will know. LOL. BTW, she said she would actually do that!
Would love to hear how others are doing on the Ocre...