mccpm wrote:... everyone seems to have their own opinions.
Back to Copaxone specifically, my stomach starts to turn when I think about it or read anything about the actual application because I really don't like needles. I am the kind of guy who passes out after a small blood test (my wife always laughs at me for this!). I run and exercise a lot so I don't have a lot of excess skin etc to inject into so that also makes me nervous especially reading some people's stories about lipoatrophy.
Here is my own opinion: I believe insulin is a major player. I believe that excess insulin is responsible for most of my MS symptoms and possibly yours. From this day forward, I encourage you to eat a healthy diet (a good idea whether or not a person has MS) – a diet that will not trigger insulin production. Many people find that diet can influence the symptoms of MS. In my opinion, this means a low-carb diet -- remove ALL trans fats (These increase insulin.); remove all sugar (including beer, wine, etc. which have sugar); and remove all artificial sweeteners, including sugar alcohols like sorbitol, xylitol, etc. (These promote insulin production, too.); and remove white flour, white bread (your wheat allergy has already helped with these two), white potatoes, white rice (in fact, all carbs so far as possible) from your diet.
Ordinarily, I suggest that people undergo a blood draw and "fasting blood insulin test," which may not be possible in your case (we don't want you to pass out!)
By the way, stress in your life (and a sleep habit of 5-6 hours a night) increases the hormone cortisol. Cortisol (and corticosteroids, like prednisone and Solu-Medrol) raise the blood sugar… and, consequently, the insulin level.
After personally using DMD's (Betaseron, Avonex, Copaxone) for more than 10 years and judging them to be ineffective, I do not believe that any currently approved MS drugs will be effective until scientists identify the CAUSE of MS.
My suspicion is that Fatty Liver Disease also contributes to MS, since visceral fat (belly fat) secretes cytokines (like poison to the internal organs), which lead to increased insulin
, which leads to inflammation which leads to more visceral fat… And the cycle goes round and round. Diet is important; in fact, you may find the account of Dr. Terry Wahls and her dramatic improvement interesting (http://www.TerryWahls.com
My hypothesis: excess insulin (hyperinsulinemia) plays a major role in MS, as developed in my initial post: http://www.thisisms.com/forum/general-discussion-f1/topic1878.html "Insulin – Could This Be the Key?"