thanks for your statement on LDN.
What does the abbreviation MJ stand for?
What leads you to the point that lower doses would have the same effect? Why do you think LDN does not have an effect on the immunesystem?
Regarding the mechanism of action I'd like to refer to this article:
In addition, increased levels of endorphins would also be expected to stimulate the immune system, promoting an overall increase in the numbers of T lymphocytes. This effect has been observed in Dr Bihari’s research. This increase in T-cell numbers apparently restores a more normal balance of the T-cells such that the effects of the disease process is reduced.
Additionally I'd also like to take Campaths sideeffect, autoimmun ITP, in regard, which is thought to be caused by an eradication of regulatory T-Cells.
Putting these two things together I think LDN does have a stregthening effect on ones immune system and (as the opposite of Campaths sideeffect) may have a substantial effect on the course of MS by restoring regulatory T-Cells.
Though there haven't been any scientificly relevant clinical trials for LDN in MS, you can read of many people (including myself) who had signifficant success with LDN, which can hardly be explained only with reduced stress levels.