what convinced your doc to prescribe you LDN?

A board to discuss Low Dose Naltrexone (LDN) as a treatment for Multiple Sclerosis

what convinced your doc to prescribe you LDN?

Postby mmpetunia » Sun Jan 27, 2013 10:36 pm

did you take her/him research? or gave a persuasive speech about how LDN would benefit you and your particular circumstances? just trying to figure out what has been working for others so that i can try it :)
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Re: what convinced your doc to prescribe you LDN?

Postby CureOrBust » Mon Jan 28, 2013 5:46 am

I am not on LDN, and did not really find it to reduce my symptoms. If Anything, it made me very stiff the following day.

I got my script for it from my GP. He had prescribed Naltrexone at full dose previously for alcohol or heroin treatments. I have known him for a while, he knew there were few treatments for my MS and so he was compassionate to my situation and the other thing that made him very comfortable with it was just how low a dose was involved. He basically thought it would do nothing, so there was no harm.

Good luck.
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Re: what convinced your doc to prescribe you LDN?

Postby Anonymoose » Mon Jan 28, 2013 7:17 am

FYI, LDN increases ACTH release. ACTH causes cortisol and aldosterone release. Cureorbust's increased stiffness might be attributable to aldosterone as it has been proven to increase muscle tension in the heart and is suspected to cause increased tension in other muscles. People seem to need to find a very specific dosage for LDN to be helpful. I think this is because it also increases release of luteinizing hormone which increases progesterone levels. Progesterone blocks aldosterone and cortisol receptors. You have to find the dosage that creates a net decrease in cortisol and aldosterone activity in order to have good results.

Personally, I wouldn't go this route. We already have enough issues with excess cortisol and aldosterone. That said, a lot of people take it so maybe it is worth it.
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Re: what convinced your doc to prescribe you LDN?

Postby Barry » Mon Jan 28, 2013 7:39 am

mmpetunia wrote:did you take her/him research? or gave a persuasive speech about how LDN would benefit you and your particular circumstances? just trying to figure out what has been working for others so that i can try it :)



I did a bit of both.

Prior to going to the appointment, I went to the only compounding pharmacy in my town and found out where they get their LDN powder, what they use for filler, how much it costs and a round about number of how many LDN scripts they fill.

I brought the doc some info found on the web that she barely looked at. Then I was brutally honest telling her that nobody knows much of anything about MS. I suggested that the way it works is this: If the Extavia the neuro is pushing seems to work, he pats himself on the back for being a genius. If it doesn't he switches drugs. Nobody knows if success or failure is just due to being in remission. I didn't think that screwing with my immune system and the long list of side effects was a good starting place.

LDN has none of the problems and stands just as good a chance of doing something good as anything else and if it doesn't seem to do anything, I'll try Extavia after 6 months of LDN.

I don't know why but my cognitive problems cleared up right away. Physically nothing has changed much with balance and numbness and all that stuff. I can live with that and I'm still popping my LDN @ 1.5 mg 8 months later.
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Re: what convinced your doc to prescribe you LDN?

Postby Azaeleaprawn » Wed Oct 01, 2014 12:28 pm

I didn't really have to do much other than ask him. He spoke to me of side effects at higher dosages in order to allow me to give an informed consent. I also told him that with my SPMS that there is really no other treatment option and him being very compassionate gave me a prescription. I'm starting at 1.5mg tonight and will see what it does for me.
Last edited by Azaeleaprawn on Fri Oct 31, 2014 12:52 am, edited 1 time in total.
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Re: what convinced your doc to prescribe you LDN?

Postby Lynn62 » Thu Oct 02, 2014 10:07 am

Please keep us posted on your LDN experience.

I have been taking 3mg for about a year now and I am trying to get my neuro to reduce my dose to 2mg.

I have noticed improvements in sleep, energy level, bladder control and brain fog but my leg stiffness is way worse than it was when I started LDN. My legs are so stiff and heavy that I walk very slow and I can't walk far. People say it is dose related and trial and error helps to figure out your correct dose, don't give up right away, it takes time.

Good luck,
Lynn

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took Avonex for 15 years
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started LDN 3 mg. 11/2013
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Re: what convinced your doc to prescribe you LDN?

Postby Azaeleaprawn » Thu Oct 02, 2014 11:46 am

So, I took my 1st dose (1.5 mg) of LDN last night and slept like a log. Stiffness in my legs is much the same but now I'll be keeping track of it . I'll post any major changes - if and when then happen, Here's hoping there'll be some good changes!
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Re: what convinced your doc to prescribe you LDN?

Postby Anunymouse » Sun Oct 05, 2014 10:58 pm

Prescription?

The first neoro i went to basically said there are 6 meds, none of them work, and all cost 3x what you make in a year. Which do you want? Paraphrasing but thats what i took out of it. The more i read the more i find that says the same thing. The "best" kills you, the 2nd best doesnt outperform d3 and barely does better than placebo. After much research i called her ref ldn and antibiotics, she said she would prescribe 1 week if i wanted and that was it. I talked to my general who i really like and he didnt want to do the long term scripts either.

So i order my own.

The first 2 days after starting both ldn and abx, i felt better than i had in years. Not just stuff from yesterday is gone better, but i dont remember feeling this good ever better. Then the abx started catching up to me.

Anyways, ive been on this route for about 8 months. My last general dr visit, he said i look really good and asked if i was on the mainstream or still "doing my own thing". After that he said that if i want scripts for anything to let him know and he'll write them. So far i dont need them but tbh I wouldnt mind not having the taste of liquid ldn in my mouth every night, so i might have him scrip the pill form eventually.

My wife says i sleep 100x better, she has spent years afraid to move because i would always "wake up". Now i just sleep.
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