I personally have never seen any negative responses to LDN in the few months I've been reading about it.
I myself have been on 3mg LDN capsules for 2 weeks now and feel better already. My pain has virtually gone, I am walking easier and sleeping all night without having to get up to use the toilet. I don't expect to be cured as it's not a cure but if it halts any more progression, then I'll be very very happy.
I obtained my LDN from USA.