Immunoglobulins and B-cells

A forum to discuss research on the origins of MS and its development.

Immunoglobulins and B-cells

Postby frodo » Mon Jul 02, 2018 3:13 am

It seems that B-cells are responsible for producing the oligoclonal Bands (OCB) that appear in MS. For some reason which I don't understand, the B-cells are clones from the same one and produce mainly three immunoglobins (Ig) in CSF: IgG, IgM and IgA.

http://n.neurology.org/content/90/15_Supplement/P1.394

Cerebrospinal Fluid IgA Levels Correlate with Disease Activity in Patients with Multiple Sclerosis; A Novel Finding (P1.394)
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