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Vitamin D: hope on the horizon for MS prevention?

Postby MSUK » Mon May 24, 2010 11:04 pm

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The worldwide prevalence and incidence of multiple sclerosis (MS) are on the increase.

The need for strategies to prevent this devastating disease is therefore greater than ever.

As highlighted in a Review in this issue of The Lancet Neurology, vitamin D deficiency might be an important modifiable risk factor for MS. This raises the question of whether population-wide supplementation programmes might be a reasonable prevention strategy.... [Read More - http://www.msrc.co.uk/index.cfm/fuseact ... ageid/1334 ]
MS-UK - http://www.ms-uk.org/
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Should Scotland introduce Vitamin D supplementation?

Postby MSUK » Tue Jun 01, 2010 1:18 am

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When Ryan McLaughlin was 14 he found himself displaying symptoms of Multiple Sclerosis.

Acutely aware of the condition as a result of his mother’s diagnosis two years previously, he was referred to Yorkhill hospital for tests.

Hoping to learn of a cure, he sought answers on the internet and came across research from Oxford University, highlighting the link between Vitamin D deficiency and MS.................

Read More - http://www.msrc.co.uk/index.cfm/fuseact ... ageid/1334
MS-UK - http://www.ms-uk.org/
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Postby tara97 » Wed Jun 02, 2010 11:01 pm

I cant say enough for D. as I cant say enough for calcium and the elctrolytes (calcium, magnesium, potassium, sodium) and the hormones that support them D, PTH, cortisol etc. I dont think we loose control of our immune system. in fact it seems to be working too well but rather I had lost control of the of these electrolytes responsible for neutralizing immune responses. I dont think any of this would happen if we had contol of this and this is our pH balence. everywhere in this world we go, our immune system responds allowing us to adapt to environmental changes and stresses. this brings us to an acidic level which must then be neutralized and brought back up to the proper pH level 7. electrolyte homeostasis
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electrolyte homeostasis why D is important

Postby tara97 » Fri Jun 04, 2010 9:53 pm

www.mgwater.com/schroll.shtml
know that if you have control of electrolyte homeostasis then you have control over your immune system.
the hormone cortisol effect the sodium/potassium exchange
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Low sunlight linked to MS onset age

Postby MSUK » Mon Jun 07, 2010 4:13 am

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Age of onset of multiple sclerosis was more than two years earlier in patients who lived in northern latitudes -- with reduced exposure to the sun in fall and winter -- during childhood, researchers found.

Low intake of vitamin D supplements was also associated with earlier onset, according to Joel Culpepper, MD, of the University of Maryland School of Medicine in Baltimore and colleagues............Read More - http://www.msrc.co.uk/index.cfm/fuseact ... ageid/1334
MS-UK - http://www.ms-uk.org/
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Vitamin D linked to poor learning performance in MS patients

Postby MSUK » Wed Jun 09, 2010 11:49 pm

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A new study shows that serum vitamin D deficiency is associated with poor learning performance among patients with multiple sclerosis (MS).

The research was presented at the Consortium of Multiple Sclerosis Centers 24th Annual Conference and the Third Joint Meeting of Americas Committee for Treatment and Research in Multiple Sclerosis.

There is some evidence that vitamin D suppresses proinflammatory cytokines, and that low levels of these cytokines could contribute to MS. Other evidence suggests that vitamin D plays a role in cognitive function in older adults. Cognitive impairment is very common in MS, but few studies have examined the relationship between serum vitamin D and cognitive deficits in this population.... Read More - http://www.msrc.co.uk/index.cfm/fuseact ... ageid/1334
MS-UK - http://www.ms-uk.org/
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Re: Vitamin D linked to poor learning performance in MS pati

Postby NHE » Thu Jun 10, 2010 12:07 pm

squiffy2 wrote:There is some evidence that vitamin D suppresses proinflammatory cytokines, and that low levels of these cytokines could contribute to MS.


Is there a typo in this article? If vitamin D suppresses proinflammatory cytokines, then this should be good for MS. I would think that high levels, not low levels, would be a contributing factor to MS.

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FDA warns of too much infant Vitamin D

Postby zap » Tue Jun 15, 2010 9:18 pm

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Postby jimmylegs » Wed Jun 16, 2010 6:56 am

warns of *risk* of overdosing infants if wrong droppers are used.
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Postby zap » Wed Jun 16, 2010 7:02 am

yeah, I'm not a parent and I don't really know how common that (dropper vitamins feeding) is, but reckoned that parents who are MS-vit-D-aware (like folks on here) might be prone to giving their kids extra Vitamin D.
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Postby gibbledygook » Wed Jun 16, 2010 8:36 am

Have the FDA conducted double-blind placebo controlled trials in Vitamin D or is it like the units of alcohol recommendations - just made up?
3 years antibiotics, 06/09 bilateral jug stents at C1, 05/11 ballooning of both jug valves, 07/12 stenting of renal vein, azygos & jug valve ballooning,
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Vitamin D-- how much? your kids & you

Postby MSdetective » Tue Jun 22, 2010 8:22 pm

My husband was diagnosed 6 months ago. In that time, I have been reading, asking questions and learning. One thing I have yet to resolve is a good answer on giving my daughter D3. Her pediatrician is clueless about MS, much less MS and vitamin D link. The pediatrician says ask the neuro. The neurologist is a terrific MS specialist, perfect for my grown husband, but he admits he knows little about pediatrics, and since technically the child is not his patient, he is a cautious to advise anything.

One thing the pediatrician and I did resolve and agree to was to change her multivitamin to something without iron! (The clueless pediatrician is onboard with CCSVI, lol.) However the vitamin D was left hanging out there.

I see 400 IU is the standard recommended for children. I will do that if nothing else... but should/could I do more?

So, are you giving your children D3? If so, how much?

It sounds like most of you are on D3 supplements yourselves... how much? Husband is on 2000 daily. That seems low for an MS patient compared to what I've read from you all here.

Thanks so much! (Sorry if this is a repeat discussion, I did search the site.)
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Postby jimmylegs » Tue Jun 22, 2010 8:57 pm

hi there and welcome :)
i think you should do more but testing is needed.
the target is 150 nmol/L. or at least 100 nmol/L.
if you need conversion numbers, google 'si units clinical data' (without quotes) and once you're on the page, scroll down to 'vitamin d3' (the 25OH kind)
Last edited by jimmylegs on Fri Jun 25, 2010 2:48 pm, edited 1 time in total.
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Postby daverestonvirginia » Wed Jun 23, 2010 6:48 am

MSdetective, I give my children 1,400 iu's a day. They get 400 from a multi-vit and I give them an extra 1000 vit d pill. I take 6,000 iu's a day. I do and have gotten my vit d level checked first every 6 months and now about once a year. I have never gotten the kids checked. I might do that at some point. Dave
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Postby shye » Fri Jun 25, 2010 8:35 am

www.vitamindcouncil.org is great source of info on Vit D
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