Conclusion:D3 is approximately 87% more potent in raising and maintaining serum 25(OH)D concentrations and produces 2- to 3-fold greater storage of vitamin D than does equimolar D2. For neither was there evidence of sequestration in fat, as had been postulated for doses in this range. Given its greater potency and lower cost, D3 should be the preferred treatment option when correcting vitamin D deficiency.
It seems that Vitamin D has a direct effect on the regulatory T lymphocyctes known as Tr1 cells. These cells keep the Th1 imnflamitory response from getting out of control.
Here is a good description of this process:
Here are some recent articles from the imunological community on the effect of Vitamin D on the immune system;
Here is a company developing cell therapy for Tr1 cells:
It appears that the immunologist are way ahead of the game in terms of a cure for MS. Vitamin D and Tr1 regulatory cells seem to be the key.
Unfortunately, it does not seem like much research or attention is being focused on this in the U.S.
goodtotalk wrote:Can you tell me where to find documented proof of that fact please if you would be so kind
While 8,000 IU's of vitamin D3 per day is a general recommendation that appears to be beneficial for most people, vitamin D experts from around the world are in agreement that the most important factor is your vitamin D serum level. There's no specific dosage level at which "magic" happens. So the take-home message is that you need to take whatever dosage required to obtain a therapeutic level of vitamin D in your blood.
Froggie wrote:I recently had my vitamin D level tested and it appears to be a little low. Can anyone recommend a reliable website that charts vitamin D levels? I'm currently taking 2000 IU's, though likely need to up it.
Froggie wrote:Thanks for the tip. No, I'm not taking zinc other than in my multi vitamin. Worth investigating, as I'm reassessing my supplement regime.
Froggie wrote:It's 11mg, though it doesn't say what form. It's a pretty generic multi, so the ingredients are likely more geared towards your average person and not someone with MS. How much vitamin D and zinc do you take?
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