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Fish oil as an adjunct therapy for depression in multiple sclerosis and Parkinson’s disease: A Randomized, Placebo-controlled Pilot Study.
IRB# 179, Principal Investigator: Lynne Shinto, ND

The MS Center of Oregon at Oregon Health & Science University is looking for people with a confirmed diagnosis of relapsing remitting MS who are suffering from depression. The purpose of the study is to determine if taking omega-3 fatty acids helps with symptoms of depression in people with MS. In addition we will determine if omega-3 fatty acids decrease blood levels of substances that are associated with MS and depression

You may be eligible to participate in the study if you meet the all of the following criteria:

• 18-85 years old
• Have a diagnosis of MS
• If using disease modifying medications, participant must be on a stable dose at least 6 months prior to enrollment
• On a stable dose of anti-depressant medication
• Have not had an MS relapse or received corticosteroid treatment 1 month prior to enrollment
• Have not eaten more than one 6 oz serving of fish per week 1 month prior to enrollment
• Have not taken fish oil or omega-3 fatty acid supplementation 1 month prior to enrollment
• Not pregnant
• Have no other significant health conditions (like coronary heart disease, uncontrolled diabetes mellitus, liver disease, severe psychiatric disorders)
• Not participating in any other studies

This is a three-month pilot study in which 60 participants will be randomly assigned to receive either fish oil capsules (which have high amounts of omega-3 fatty acids) or placebo oil capsules.

The study requires 3 visits to OHSU. The research study will pay for all costs associated with the participation in this study. You will be responsible for any expenses that have to do with other aspects of your participation such as childcare and transportation.
If you meet the eligibility requirements described above and are interested in participating in this study please call Lilia Alvarez at (503) 494-3549.